Flavonoids and their glycosides, including anthocyanins

Veitch, Nigel C.; Grayer, Renée J.

doi:10.1039/c1np00044f

Cited by 254 publications

(117 citation statements)

References 471 publications

(760 reference statements)

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“…Fruits and vegetables supply a number of micronutrients, such as minerals, fibres and vitamins, as well as a whole series of compounds called phytochemicals, among which are the secondary metabolites of a phenolic nature, called polyphenols [1][2][3]. Phenolic compounds have attracted the attention of researchers for decades [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Capacity of Anthocyanin Pigments

Martín¹,

Kuskoski²,

Navas³

et al. 2017

Flavonoids - From Biosynthesis to Human Health

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Anthocyanins are a family of natural pigments classified into the group of flavonoids, considered to be responsible for the color and taste of many fruits and vegetables, i.e. berries. Anthocyanins are common components of the human diet. Besides their interest as colorant because of their coloring properties, the study of anthocyanin compounds stems from their wide applicability in the prevention and even in the treatment of various human diseases. However, various aspects of the pharmacological roles of anthocyanins remain in the dark, having still several obstacles to the development of robust diets or prescribing lines on consumption of anthocyanins. The chemical structure of anthocyanins determines in large measure its capacity and efficacy as an antioxidant agent. In this study, the following aspects are reviewed: the antioxidant effect of anthocyanin pigments; the oxidative stress, the bioavailability after intake and biological aspects of anthocyanins, the method for measuring the antioxidant activity of anthocyanins, the relationship between structure and activity; and the influence of the anthocyanins in the antioxidant activity of wines. Finally an overview of some potential uses in food industry is attempted mainly focusing in the anthocyanin encapsulation topic. Attention has been paid to the more recent publications in the field.

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Section: Introductionmentioning

confidence: 99%

Antioxidant Capacity of Anthocyanin Pigments

Martín¹,

Kuskoski²,

Navas³

et al. 2017

Flavonoids - From Biosynthesis to Human Health

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“…Their structural variation, reflected by more than 9,000 compounds reported to date, is achieved through "decorative" steps, such as glycosylations, acylations, prenylations, methylations, hydroxylations, and combinations of the above (2). Because chemodiversity correlates with a diversity of function, specific strategies and mechanisms of chemical structural modification are of great interest (3,4).…”

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confidence: 99%

The Roles of a Flavone-6-Hydroxylase and 7-O-Demethylation in the Flavone Biosynthetic Network of Sweet Basil

Berim

Gang

2013

Journal of Biological Chemistry

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Background: Late steps of lipophilic flavone biosynthesis in mints are unknown. Results: CYP82D monooxygenases catalyze 6-hydroxylation of 7-O-methylated precursor, whose 7-methyl group is subsequently removed by demethylation in basil but not in peppermint. Conclusion: Flavone biosynthesis in basil involves an unusual loop. Significance: Novel mechanisms elucidated in basil suggest a new hypothesis for similar metabolic networks in other plants.

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“…The phenylpropanoid pathway gives rise to a large range of phenolic compounds, including flavonoids, lignins, lignans, coumarins, stilbenes, and sinapate esters (Veitch and Grayer, 2008;Petersen et al, 2010), which are involved in many aspects of plant physiology. Phenylpropanoids have roles related to photoprotection (Kim et al, 2008), cross talk with hormones (Besseau et al, 2007;Yuan et al, 2013), Rhizobium spp.…”

mentioning

confidence: 99%

A Kelch domain-containing F-box coding gene negatively regulates flavonoid accumulation in Cucumis melo L.

Feder

Burger²,

Gao

et al. 2015

Plant Physiol.

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The flavonoids are phenylpropanoid-derived metabolites that are ubiquitous in plants, playing many roles in growth and development. Recently, we observed that fruit rinds of yellow casaba muskmelons (Cucumis melo 'Inodorous Group') accumulate naringenin chalcone, a yellow flavonoid pigment. With RNA-sequencing analysis of bulked segregants representing the tails of a population segregating for naringenin chalcone accumulation followed by fine mapping and genetic transformation, we identified a Kelch domain-containing F-box protein coding (CmKFB) gene that, when expressed, negatively regulates naringenin chalcone accumulation. Additional metabolite analysis indicated that downstream flavonoids are accumulated together with naringenin chalcone, whereas CmKFB expression diverts the biochemical flux toward coumarins and general phenylpropanoids. These results show that CmKFB functions as a posttranscriptional regulator that diverts flavonoid metabolic flux.

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Flavonoids and their glycosides, including anthocyanins

Cited by 254 publications

References 471 publications

Antioxidant Capacity of Anthocyanin Pigments

Antioxidant Capacity of Anthocyanin Pigments

The Roles of a Flavone-6-Hydroxylase and 7-O-Demethylation in the Flavone Biosynthetic Network of Sweet Basil

A Kelch domain-containing F-box coding gene negatively regulates flavonoid accumulation in Cucumis melo L.

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