Flavonoid–DNA binding studies and thermodynamic parameters

Studies of the interactions of 4-carboxyl-2,6-dinitrophenylazohydroxynaphthalenes with CT-DNA in aqueous medium

“…Virtually all the interaction of small molecules with DNA is expected to be a reversible process, an association of some type, so at higher temperatures, the complex formed between DNA and the dye molecules may not remain compact as it was at lower temperature. Increase in temperature changes the geometrical orientation of DNA and the complexes formed may become loose with dissociation setting in [34]. For AZ-04, an anomalous behaviour as reported for the mole ratio determination was once again observed.…”

A Ft-Ir Spectroscopic Study on Hydroalcohalic Extract of Amalakyadi-Gana (Compound Formulation)

“…[11] Not solely this, these plants are also used potentially in treatment of intestinal disorders. [9][10][12][13][14][15] A Weak peak appears at 1119 cm-1 is because of absorption of polysaccharides.…”

Studies on DNA Interaction with 2(3),9(10), 16(17), 23(24)‐Tetrakis 2((4‐Phenoxyphenyl) Diazeylbenzoic acid)phthalocyaninato Zinc (II) Compound

“…DNA has been an important target for treatment of genetic disorders such as cancer. The study of the interaction of metallophthalocyanine compounds with DNA not only provides an opportunity to understand the interactive mechanisms of some antitumor, but also allows the design of new DNA targeted metallophthalocyanine compounds ,. Owing to the principal function of DNA in transcription and replication, the DNA molecule has been a major target for antibiotic and anticancer drugs .…”