Flavonoid Compounds, Tannins, Lignins and, Related Compounds

Geissman, T. A.

doi:10.1016/b978-1-4831-9718-0.50018-7

Cited by 83 publications

(52 citation statements)

References 7 publications

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“…A great number of these agents already exist and their actions on microorganisms are due to the presence of certain substances in plants. Plants are known to have special ability to synthesize aromatic substances, most of which are phenols or their derivatives [1]. Though some of these compounds may not have any discernible physiological roles in the plants in which they occur, many of them have significant biological effects on animals.…”

Section: Introductionmentioning

confidence: 99%

Isolation and Elucidation of Three Triterpenoids and Its Antimycobacterial Activty of Terminalia Avicennioides

Mann¹,

Ibrahim²,

Oyewale³

et al. 2012

AJOC

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Terminalia avicennioides Guill. & Perr. (Combretaceae) has been traditionally used as traditional medicine for centuries in Nupeland, North Central Nigeria for the treatment of respiratory diseases such as tuberculosis and cough. This study evaluates the in vitro antimycobacterial activities of the isolated compounds in order to support the therapeutic use of T. avicennioides for treating these infectious diseases. Chemical investigation by bioassay-guided fractionation led to the isolation of three triterpenoids namely, arjunolic acid (1), α-amyrin (2) and 2, 3, 23-trihydroxylolean-12-ene (3). Among them, arjunolic acid manifested the most potent antimycobacterial activity against a strain of Mycobacterium bovis (BCG). Structure elucidation of the isolated compounds were based primarily on the analysis of 1-D and 2-D NMR spectral data including HMQC, HMBC, COSY and NOESY correlations, as well as comparison with reported authentic data of arjunolic acid, α-amyrin and 2, 3, 23-trihydroxylolean-12-ene. To the best of our knowledge, this is the first time these compounds (1-3) are reported from this plant. The present result further confirms the value of ethnopharmacological investigations into traditional herbs for leads for potential drug development.

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Section: Introductionmentioning

confidence: 99%

Isolation and Elucidation of Three Triterpenoids and Its Antimycobacterial Activty of Terminalia Avicennioides

Mann¹,

Ibrahim²,

Oyewale³

et al. 2012

AJOC

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“…Plants have limitless ability to synthesize aromatic substances, mostly phenols or their oxygen-substituted derivatives (Geisssman, 1963). Most of the natural products are secondary metabolites and about 12,000 of such products have been isolated so far.…”

Section: Introductionmentioning

confidence: 99%

Qualitative and Quantitative Phytochemical analysis of Moringa concanensis Nimmo

Santhi¹,

Sengottuvel²

2016

Int.J.Curr.Microbiol.App.Sci

134

106

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“…plant especially leaves possess antibacterial properties due to presence of tannins and flavonoids [28,29]. This Plant also synthesize huge amount of aromatic compound among which phenols or their oxygensubstituted derivatives are predominant [30]. These compounds provide protection against microbes for the plant [31].…”

Section: Discussionmentioning

confidence: 99%

Anti-bacterial Profiling of Launaea sarmentosa (Willd.) and Bruguiera Cylindrical (L.): Two Distinct Ethno Medicinal Plants of Bangladesh

Millat¹,

Islam²,

Hussain³

et al. 2017

Eur J Exp Bio

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Aim: The present study was commenced to investigate the methanolic extracts of Launaea sarmentosa (Willd.) and Bruguiera cylindrical (L.) for antibacterial properties. Launaea sarmentosa (Willd.) is a plant of Asteraceae family while Bruguiera cylindrical (L.) belongs to the family of Rhizophoraceae. Materials and Method:The study was performed by disc diffusion method. Results:Crude methanolic extracts of both Launaea sarmentosa (Willd.) and Bruguiera cylindrical (L.) at various concentration were used for antibacterial screening. The methanolic extracts of Launaea sarmentosa (Willd.) produced good antibacterial activities against gram negative (-ve) bacteria and were resistant against gram positive (+ve) bacteria whereas crude methanolic extracts of Bruguiera cylindrical (L.) were resistant against both gram positive (+ve) and gram negative (-ve) bacteria. Conclusion:Further work especially bioassay-guided fractionation may be avouched in order to isolate and characterize the antibacterial active constituents responsible for the antibacterial property.

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Flavonoid Compounds, Tannins, Lignins and, Related Compounds

Cited by 83 publications

References 7 publications

Isolation and Elucidation of Three Triterpenoids and Its<b> Antimycobacterial </b><b>Activty </b>of Terminalia Avicennioides

Isolation and Elucidation of Three Triterpenoids and Its<b> Antimycobacterial </b><b>Activty </b>of Terminalia Avicennioides

Qualitative and Quantitative Phytochemical analysis of Moringa concanensis Nimmo

Anti-bacterial Profiling of Launaea sarmentosa (Willd.) and Bruguiera Cylindrical (L.): Two Distinct Ethno Medicinal Plants of Bangladesh

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