Flavones and flavone glycosides from Halophila johnsonii

Meng, Yanhui; Krzysiak, Amanda J.; Durako, Michael J.; Kunzelman, J. I.; Wright, Jeffrey L. C.

doi:10.1016/j.phytochem.2008.07.007

Cited by 40 publications

(27 citation statements)

References 16 publications

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“…Four flavones namely, luteolin, apigenin, luteolin-3-glucoronide and luteolin-4-O-glucoronide were identified from the ethanol extract of air dried Enhalus acoroides from South China Sea 44 . Seven new flavonoid glycoside along with five flavones, and three flavonoid glycosides from Halophila johnsonii 45 and malonylated flavone glycoside derivatives from Halophila stipulaceae 46 suggest that seagrasses are comparatively stronger in natural product synthesis in their stressful environment. Significantly higher flavonoid amounts were observed in the leaves of intertidal and subtidal H. johnsonii when compared to the leaves of intertidal H. decipiens 47 .…”

Section: 15mentioning

confidence: 99%

Bioactive natural products from marine angiosperms: abundance and functions

Subhashini

Dilipan

Thangaradjou

et al. 2013

Nat. Prod. Bioprospect.

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This review explores the natural products of seagrass that are to be exploited for their bioactive potential. Beside from portraying the presence of a wide array of secondary compounds such as phenols, flavonoids, sterols and lipids from different seagrass species, the focus is on novel natural products projecting towards their biological applications. Though there are a significant number of reports on the abundance of secondary metabolites from seagrass and their bioactive derivatives, only a small number of reports explore their functional and defensive characteristics. Efforts have been made to collate the available information on seagrass natural products and clarify their function and metabolic pathway's. It is emphasized that metabolic profiling of seagrass should be extensively progressed to obtain a deeper knowledge about the specific roles of each natural product. The investigation of seagrass natural products for their bioactive potential would most likely result in the detection of surprising and unexpected novel chemical structures and clinical leads that may be useful to mankind.Keywords: natural products, phenolic compounds, phenylpropanoid derivatives, seagrasses, secondary metabolites Seagrasses-the Marine AngiospermsSeagrasses, a functional group of flowering plants rooted in the world's coastal oceans, are well known for their secondary metabolites. The current comprehensive review on "Bioactive natural products from marine angiosperms'' was performed in such a way that recent discoveries in the field of seagrass secondary metabolism need to be reviewed. In this review is not possible to detail in a just few pages the full gamut of studies, since our understanding of natural products from seagrasses has increased markedly in the last few decades. Several studies have documented the abundance of these natural metabolites in seagrasses and some have focused on their bioactive potential. Though there are probably 72 species of seagrasses worldwide, only a few have been explored for their natural products and their determinant role. Recently, the secondary metabolites of P. oceanica were compiled 1 , appraised and were summarized into 51 natural products including phenols, phenylmethane, phenylethane, phenylpropane derivatives and their esters, chalkones and flavonoids. These chemical compounds synthesized by secondary metabolic pathways are not involved in the normal growth, development or reproduction but usually have roles in adaptation processes under stress conditions.A severe or long lasting stress factor could induce an excessive shift between primary and secondary metabolism and consequently, a diversion of essential available resources from growth to defense 2 , since the products of primary metabolism are the precursors for secondary metabolic pathways. The topics provided in this paper are limited to seagrass secondary metabolism although it has become clear that a clear line between primary and secondary metabolism cannot be drawn. Hence, the present review aims to collate th...

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Section: 15mentioning

confidence: 99%

Bioactive natural products from marine angiosperms: abundance and functions

Subhashini

Dilipan

Thangaradjou

et al. 2013

Nat. Prod. Bioprospect.

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“…It has been also demonstrated that various flavonoids (7,4'-dimethoxy-apigenin, isoramnetin-3-O-rutinoside, isoramnetin-3-O-glucoside, kaempferol-3-O-glucoside, hyperin), phenylpropanoids (verbascoside, 5,6,7,4'-tetrahydroxyflavone-7-O-(6"-O-[E]-coumaroyl)-β-glucopyranoside, 5,6,7,4'-tetrahydroxyflavone-7-O-(6"-O-[E]-caffeoyl)-β-glucopyranoside) produced significant antinociceptive and/or anti-inflammatory activities (Hasan et al, 2012;Albacha et al, 2003;Meng et al, 2008;Julião et al, 2010). Hence, the presence of flavonoids and phenylpropanoids may be contributory to the anti-inflammatory activity of EtOAc extract from P. alaschanica.…”

Section: Discussionmentioning

confidence: 99%

“…The HPLC chromatogram is as shown in Figure 2, which mainly contained eight peaks and named as peaks 1 to 8. Subsequently, the peaks 1 to 8 were directly identified by the spectroscopic methods, including 1 H NMR (Table 1), 13 C NMR (Table 2) techniques, and by comparison with those reported in the literature (Hasan et al, 2012;Albacha et al, 2003;Meng et al, 2008;Julião et al, 2010).…”

Section: Hplc Analysis and Nmr Identification Of Hplc Peaksmentioning

confidence: 99%

“…Recently, the anti-inflammatory effects of the EtOAc extract of P. alaschanica was studied by using eggalbumin-induced and carrageenan-induced rats. Moreover, a systematic chemical study was conducted on the EtOAc extract of P. alaschanica, which resulted in the isolation of phenylpropanoids and flavonoids (Hasan et al, 2012;Albacha et al, 2003;Meng et al, 2008;Julião et al, 2010) from the plant for the first time. This paper describes the HPLC analysis and the antiinflammatory activity of the EtOAc extract of P. alaschanica.…”

Section: Introductionmentioning

confidence: 99%

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Anti-inflammatory effect and high performance liquid chromatography (HPLC) analysis of the EtOAc extract from Panzeria alaschanica

Wang¹,

Hu²,

Shao³

et al. 2015

Afr. J. Pharm. Pharmacol.

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The aerial parts of Panzeria alaschanica are used to treat pelvic inflammation and chronic pelvic inflammation. The anti-inflammatory effects of P. alaschanica have been well known in folk medicine, which suggest that extracted components from P. alaschanica could potentially treat inflammatory disease. The aim of this study was to discover the bioactive compounds of P. alaschanica. To achieve this, ethyl acetate (EtOAc) extract was extracted from the aerial parts of P. alaschanica and the antiinflammatory effects were investigated against inflammation induced by carrageenan and egg-albumin in rats. At the doses used, EtOAc extract (

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“…Chicoric acid and caftaric acid were identified in detrital and living leaves of the tropical seagrass Syringodium filiforme making this abundant renewable raw material of interest for pharmaceutical purposes and food industries [45]. Phytochemical investigations revealed the presence of unidentified sulfated phenolic compounds from nine different species of Halophila [43], unidentified sulfated and nonsulfated flavones from the Halophila ovalis/Halophila minor complex [35], flavones and flavone glycosides from Halophila johnsonii [46], as well as malonylated flavonoid derivatives in the seagrass Halophila stipulacea [47]. Production of phenolic compounds depends on the environmental conditions.…”

Section: Occurrence Of Phenolic Acids In Seagrassesmentioning

confidence: 99%

Highlights in Seagrasses’ Phylogeny, Physiology, and Metabolism: What Makes Them Special?

Papenbrock

2012

ISRN Botany

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The marine seagrasses form an ecological and therefore paraphyletic group of marine hydrophilus angiosperms which evolved three to four times from land plants towards an aquatic and marine existence. Their taxonomy is not yet solved on the species level and below due to their reduced morphology. So far also molecular data did not completely solve the phylogenetic relationships. Thus, this group challenges a new definition for what a species is. Also their physiology is not well understood due to difficult experimental in situ and in vitro conditions. There remain several open questions concerning how seagrasses adapted secondarily to the marine environment. Here probably exciting adaptation solutions will be detected. Physiological adaptations seem to be more important than morphological ones. Seagrasses contain several compounds in their secondary metabolism in which they differ from terrestrial plants and also not known from other taxonomic groups. Some of these compounds might be of interest for commercial purposes. Therefore their metabolite contents constitute another treasure of the ocean. This paper gives an introduction into some of the most interesting aspects from phylogenetical, physiological, and metabolic points of view.

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Flavones and flavone glycosides from Halophila johnsonii

Cited by 40 publications

References 16 publications

Bioactive natural products from marine angiosperms: abundance and functions

Bioactive natural products from marine angiosperms: abundance and functions

Anti-inflammatory effect and high performance liquid chromatography (HPLC) analysis of the EtOAc extract from Panzeria alaschanica

Highlights in Seagrasses’ Phylogeny, Physiology, and Metabolism: What Makes Them Special?

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