Flap prefabrication using high-density porous polyethylene in an animal model – an experimental study

Krakowczyk, Łukasz; Maciejewski, Adam; Szymczyk, Cezary; Grajek, Maciej; Stobiecka, Ewa; Półtorak, Stanisław

doi:10.12659/msmbr.889214

Cited by 3 publications

(3 citation statements)

References 16 publications

(10 reference statements)

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“…The definitive treatment of the disease is removing the sinus cavity with the sinus tract. For this, many methods are used, from excision and leaving the wound open or not closing it [ 11 , 12 ], to various flap methods (rhomboid, Limberg, V-Y advancement flap, Z-plasty, W-plasty) [ 13 – 21 ]. An ideal operation should be simple, hospital stay should be short, pain should be minimal, and there should be low recurrence rates [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Application of fasciocutaneous V-Y advancement flap in primary and recurrent sacrococcygeal pilonidal sinus disease

et al. 2014

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BackgroundPilonidal sinus disease is a common disease of young adults, which most frequently occurs in the sacrococcygeal region on the skin’s midline. Various procedures, ranging from simple incision and curettage to complex flaps for natal cleft obliteration, have been described in the literature.Material/MethodsWe aimed to present the dermographic characters, post-operative complications, length of stay in hospital, time of return to daily activities, and recurrence rates of the patients in which we applied sinus excision and fasciocutaneous V-Y advancement flap due to primary complicated or recurrent sacrococcygeal pilonidal sinus disease.ResultsPatients with primary complicated and recurrent pilonidal sinus received a fasciocutaneous V-Y advancement flap in the general surgery service of our hospital. Eleven patients had recurrent disease. Thirty-seven patients received a unilateral V-Y flap and 8 patients received a bilateral V-Y flap. None of the patients had post-operative flap necrosis or wound opening. Two of the patients had a self-draining simple seroma and 3 of the patients had delayed wound healing in the perianal region of the incision, which was treated with dressing. The mean time required to return to daily activities was 7 days, and return to work took 17 days. In the mean 25-month follow-ups of the patients, no recurrences were detected.ConclusionsWe think that fasciocutaneous V-Y advancement flap is an easily learned and practicable method that reduces the recurrences in the patients with primary complicated and recurrent pilonidal sinus, length of stay in hospital, and time to return to daily activities and work in the post-operative period.

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Section: Discussionmentioning

confidence: 99%

Application of fasciocutaneous V-Y advancement flap in primary and recurrent sacrococcygeal pilonidal sinus disease

et al. 2014

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“…However, the biomechanical behavior of lumbosacral reconstruction for sacrectomy was not well documented. Since being first introduced by Gokaslan [ 5 ] in 1997 with development of flap surgery skills [ 6 , 7 ], MGT has become one of the most common methods in lumbosacral reconstruction for sacrectomy. In this study, we evaluated MGT reconstruction for partial sacrectomy using a finite element analysis, which is an effective procedure for biomechanically evaluating a reconstruction in detail.…”

Section: Discussionmentioning

confidence: 99%

Finite element analysis of lumbosacral reconstruction after partial sacrectomy

Cai

2014

Med Sci Monit

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BackgroundThe biomechanical property of MGT for patients who underwent partial sacrectomy is not well documented, so this study aimed to investigate biomechanical property of lumbosacral reconstruction after partial sacrectomy.Material/MethodsThree 3-dimensional finite element models of lumbosacral region were established: 1) an intact model (INT), 2) a defective model in which partial sacrectomy was performed cephalad to S1 foramina (DEF), and 3) a reconstructed model (REC).ResultsDisplacements of anchor point on L3 vertebrae in INT, DEF, and REC model were 6.63 mm, 10.62 mm, 4.29 mm (titanium), and 3.86mm (stainless steel), respectively. Stress distribution of the instrument in REC model showed excessive concentration on the caudal spinal rod, which may cause rod failure between spine and ilia. Maximum von Mise stress of the stainless steel instrument was higher than titanium instruments, and values of stress of the anchor point around the sacroiliac joint in the REC model were 26.4MPa with titanium instruments and 23.9 MPa with stainless steel instruments.ConclusionsLumbosacral reconstruction can significantly increase stiffness of the spinopelvis of patients who underwent partial sacrectomy. However, the rod between L5 and ilia is the weakest region of all instruments. Stainless steel instruments have higher risk of rod failure and are less suitable for lumboiliac arthrodesis than titanium instruments.

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“…Vascular induction by implantation of a pedicle allowed designing the flaps in discrete donor sites or in areas of skin excess. 71 Establishing new flaps with any desired anatomical component is possible in regions that do not have defined axial vessels.…”

Section: General Mechanism For Preservation Of Ex Vivo Organ Systemsmentioning

confidence: 99%

Engineering a microcirculation for perfusion control of ex vivo–assembled organ systems: Challenges and opportunities

Kottamasu

Herman

2018

J Tissue Eng

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Donor organ shortage remains a clear problem for many end-stage organ patients around the world. The number of available donor organs pales in comparison with the number of patients in need of these organs. The field of tissue engineering proposes a plausible solution. Using stem cells, a patient’s autologous cells, or allografted cells to seed-engineered scaffolds, tissue-engineered constructs can effectively supplement the donor pool and bypass other problems that arise when using donor organs, such as who receives the organ first and whether donor organ rejection may occur. However, current research methods and technologies have been unable to successfully engineer and vascularize large volume tissue constructs. This review examines the current perfusion methods for ex vivo organ systems, defines the different types of vascularization in organs, explores various strategies to vascularize ex vivo organ systems, and discusses challenges and opportunities for the field of tissue engineering.

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Flap prefabrication using high-density porous polyethylene in an animal model – an experimental study

Cited by 3 publications

References 16 publications

Application of fasciocutaneous V-Y advancement flap in primary and recurrent sacrococcygeal pilonidal sinus disease

Application of fasciocutaneous V-Y advancement flap in primary and recurrent sacrococcygeal pilonidal sinus disease

Finite element analysis of lumbosacral reconstruction after partial sacrectomy

Engineering a microcirculation for perfusion control of ex vivo–assembled organ systems: Challenges and opportunities

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