Flaccid quadriparesis with raised creatine kinase in Guillain-Barré syndrome: a case report with review of literature

Abstract

Guillain-Barré syndrome (GBS) is an acute and fulminant polyradiculoneuropathy that is autoimmune in nature and characterized by acute flaccid paralysis, with or without sensory abnormalities. GBS is predominantly classified as demyelinating and axonal types. The three common subtypes are acute inflammatory demyelinating polyradiculoneuropathy, acute motor axonal neuropathy (AMAN), and acute motor and sensory axonal neuropathy (AMSAN) [1]. Creatine kinase (CK) catalyzes the breakdown of creatine and adenosine triphosphate into phosphocreatine and