Aerospace panels are commonly restrained on complex inspection fixture jigs during the measurement process. Forces used to restrain the parts are also monitored as mandated by thier functional requirements. Given the difficulties in measuring these types of parts, this paper reviews the available fixtureless inspection methods with a focus on the challenges of their implementation, and their aptitude to be used to estimate the profile and the necessary restraining forces of an aerospace panel. To perform this investigation, finite element analysis is used to predict the constrained shape of four (4) simulated free-state aerospace panels, with two different type of boundary conditions, in five scenarios. From those analyses, the importance and limits of current finite element boundary setting methods embedded in fixtureless inspection methods for nonrigid parts are highlighted.