Fixed drug eruption due to amoxicillin and quinolones

Guevara, Lina Vanessa Ponce; Laffond, Elena; Bara, María Teresa Gracia; Ruiz, Amanda Miguel González; Rodilla, Esther Moreno

doi:10.1016/j.anai.2012.10.022

Cited by 7 publications

(2 citation statements)

References 6 publications

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“…It can be caused by many different drug classes, including non-steroidal anti-inflammatory drugs, acetaminophen, antibiotics, antimalarials, and barbiturates [ 1 ]. Among antibiotics, the most common offenders are tetracyclines, sulfamethoxazole, penicillin, and floroquinolone [ 2 , 5 ]. Sulfamethoxazole is responsible for the largest number of FDE worldwide [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…When there are multiple suspected agents, additional testing can be done through patch testing or with drug challenge [ 1 ]. While patch testing is considered safer [ 10 ], oral drug challenge is often used to identify antibiotics, given the high rate of false negatives with patch testing due to issues such as low penetrance and low concentration of drug used during patch testing [ 5 ]. As prevention is the mainstay for managing FDE, it is crucial to identify the drug causing the reaction.…”

Section: Discussionmentioning

confidence: 99%

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Fixed Drug Eruption to Trimethoprim-Sulfamethoxazole and Doxycycline

Long

Wong

Burns

2021

Cureus

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Fixed Drug Eruption to Trimethoprim-Sulfamethoxazole and Doxycycline

Long

Wong

Burns

2021

Cureus

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Update on Quinolone Allergy

Doña

Moreno

Pérez‐Sánchez

et al. 2017

Curr Allergy Asthma Rep

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Allergic reactions to quinolones can be immediate or delayed, being anaphylaxis and maculopapular exanthema respectively the most frequent clinical entities. A precise diagnosis is particularly difficult since clinical history is often unreliable, skin tests can induce false-positive results, and commercial in vitro test are not well validated. Therefore, drug provocation testing is considered the gold standard to establish diagnosis, which is not a risk-free procedure. Cross-reactivity between quinolones is difficult to predict due to the small number of patients included in the few published studies. Moreover, hypersensitivity to quinolones has also been associated with beta-lactam and neuromuscular blocking agent allergies, although further studies are needed to understand the underlying mechanisms. Avoidance of the culprit quinolone is indicated in patients with a diagnosis of hypersensitivity to these drugs. When quinolone treatment is the only therapeutic option available, desensitization is necessary. This review summarizes the complex diagnostic approach and management of allergic reactions to quinolones.

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Amoxicillin/fluoroquinolones

2013

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Fixed drug eruption due to amoxicillin and quinolones

Cited by 7 publications

References 6 publications

Fixed Drug Eruption to Trimethoprim-Sulfamethoxazole and Doxycycline

Fixed Drug Eruption to Trimethoprim-Sulfamethoxazole and Doxycycline

Update on Quinolone Allergy

Amoxicillin/fluoroquinolones

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