2003
DOI: 10.1034/j.1600-0676.2003.01804.x
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Five‐year survival predictive factors in patients with excessive alcohol intake and cirrhosis. Effect of alcoholic hepatitis, smoking and abstinence

Abstract: In hospitalised patients with excessive alcohol intake and cirrhosis: (1) age, liver failure, gastrointestinal bleeding, concomitant viral B or C infection and persistent alcohol intake are independent poor prognostic markers, (2) smoking may contribute to the aggravation of cirrhosis, and (3) alcoholic hepatitis, being a potentially reversible cause of liver failure, has a favourable prognostic significance.

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Cited by 235 publications
(169 citation statements)
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“…11,62,68 Underlying aetiology may be a significant factor in this variability, with viral cirrhoses being detected at an earlier stage 69 and patients with cirrhosis of alcoholic origin presenting with more advanced failure. 11,60 Epidemiology and natural history of hepatocellular carcinoma Hepatocellular carcinoma (HCC) is the name given to tumours arising from liver cells (hepatocytes). HCC is considered to be the most common type of primary liver tumour, although data from the office for National Statistics (ONS) show that, in England, intrahepatic bile duct cancer (cholangiocarcinoma) may be more common, 70 certainly among women.…”
Section: Incidence Of Decompensationmentioning
confidence: 99%
“…11,62,68 Underlying aetiology may be a significant factor in this variability, with viral cirrhoses being detected at an earlier stage 69 and patients with cirrhosis of alcoholic origin presenting with more advanced failure. 11,60 Epidemiology and natural history of hepatocellular carcinoma Hepatocellular carcinoma (HCC) is the name given to tumours arising from liver cells (hepatocytes). HCC is considered to be the most common type of primary liver tumour, although data from the office for National Statistics (ONS) show that, in England, intrahepatic bile duct cancer (cholangiocarcinoma) may be more common, 70 certainly among women.…”
Section: Incidence Of Decompensationmentioning
confidence: 99%
“…High age and continuous alcohol consumption of more than 10 g ethanol per day were independent predictors of a poor prognosis [74]. The prognostic importance of abstinence was demonstrated in both Child-Pugh A/B and Child-Pugh C patients [75].…”
Section: Antifibrotic Therapymentioning
confidence: 88%
“…Three factors greatly condition the long-term prognosis of AH that are scarcely emphasized in the paper by Bargalló et al These include alcohol withdrawal, presence of cirrhosis, and response to steroid therapy. Withdrawal is the single most important predictor in AH once the initial stage is over, and is also essential when considering transplantation (19). Therefore, dependency therapy should be initiated during hospitalization to be followed by stringent monitoring for at least two years after discharge.…”
Section: Establishing Prognosis In Alcoholic Hepatitismentioning
confidence: 99%