Five-year review of ocular Neisseria gonorrhoeae infections presenting to ophthalmology departments in Greater Glasgow &amp; Clyde, Scotland

Butler, Laura; Shah, Manaim; Cottom, Laura; Winter, Andrew; Lockington, David

doi:10.1038/s41433-021-01658-z

Cited by 3 publications

(3 citation statements)

References 18 publications

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“…Virulence factors include Type IV pili, lipooligosaccharides, porin, opacity proteins, and efflux pumps [ 288 ]. In their five-year retrospective review, Butler et al [ 289 ] reported 15 cases of ocular gonococcal infections. The most common presenting features reported were a purulent discharge (93% of cases), hemorrhagic conjunctivitis (67% of cases), and pre-sepal cellulitis (60% of cases).…”

Section: Hapax Legomenon Isolatesmentioning

confidence: 99%

“…All patients were treated with systemic antibiotics and topical chloramphenicol or ofloxacin. Corneal involvement was reported in 33% of cases, but there was no “significant” corneal melting or perforation [ 289 ]. Because corneal ulceration can rapidly progress to corneal melting and perforation, treatment must be prompt and effective [ 290 , 291 ].…”

Section: Hapax Legomenon Isolatesmentioning

confidence: 99%

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Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

Astley,

Mursalin,

Coburn

et al. 2023

Microorganisms

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Ocular infections can be medical emergencies that result in permanent visual impairment or blindness and loss of quality of life. Bacteria are a major cause of ocular infections. Effective treatment of ocular infections requires knowledge of which bacteria are the likely cause of the infection. This survey of ocular bacterial isolates and review of ocular pathogens is based on a survey of a collection of isolates banked over a ten-year span at the Dean McGee Eye Institute in Oklahoma. These findings illustrate the diversity of bacteria isolated from the eye, ranging from common species to rare and unique species. At all sampled sites, staphylococci were the predominant bacteria isolated. Pseudomonads were the most common Gram-negative bacterial isolate, except in vitreous, where Serratia was the most common Gram-negative bacterial isolate. Here, we discuss the range of ocular infections that these species have been documented to cause and treatment options for these infections. Although a highly diverse spectrum of species has been isolated from the eye, the majority of infections are caused by Gram-positive species, and in most infections, empiric treatments are effective.

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Section: Hapax Legomenon Isolatesmentioning

confidence: 99%

Section: Hapax Legomenon Isolatesmentioning

confidence: 99%

Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

Astley,

Mursalin,

Coburn

et al. 2023

Microorganisms

View full text Add to dashboard Cite

show abstract

“…It is rarely considered in older children or adolescents. Since it is relatively rare in adolescents, clinical diagnosis may be delayed [ 2 , 3 ]. Inappropriate treatment timing means that gonococcal conjunctivitis could progress in a rapid and fulminant fashion, threatening patients’ vision.…”

mentioning

confidence: 99%