Five-Year Prospective Clinical Evaluation of Highly Crystalline HA MP-1–Coated Dental Implants

Abstract

Contemporary plasma-sprayed hydroxylapatite (HA) coatings with high crystalline content are much more resistant to in vivo degradation than HA coatings of a decade ago but reportedly exhibit reduced wettability, which could potentially negatively affect tissue adhesion and long-term clinical outcome. The present prospective study was undertaken to determine if highly crystalline HA MP-1-coated implants could meet a minimum 5-year implant success rate standard of 85% in view of their previously reported decreased wettability. Study subjects were consecutive patients with 1 or more missing teeth in the maxillary and/or mandibular jaw who presented in 3 university dental clinics and 1 private dental practice. A total of 120 patients were treated per protocol and successfully restored with implant-supported prostheses. Four implants failed in 3 patients and were withdrawn from the study. There were no other irresolvable adverse events. Cumulative implant success at 5 years was 97% (n = 184 implants in 88 patients), which exceeded the 85% standard for implant success after 5 years of clinical function.

Long‐term survival of calcium phosphate‐coated dental implants: a meta‐analytical approach to the clinical literature

“…; Thierer et al. ) and are summarized in Tables and . No additional publications were identified by manual search for inclusion.…”

Effect of loading time on marginal bone loss around hydroxyapatite-coated implants

“…HAPTITE (Dentis Co., Ltd., Daegu, Korea) claimed to have resolved uneven coating and desquamation problems by reducing coating thickness to 2 µm using an ultra-thin coating technique applied in vacuum at room temperature22. The Zimmer TSV-HA used in this study recorded a 97% success rate because it increased the HA crystallization rate to 97% with the application of plasma coating over HA and special MP-1 process using compressed hydration heat treatment23. Crystallization rate is an important factor in HA-coated implants because a non-crystallized HA-coated surface may melt, break, or disintegrate and cause the implant to fail.…”

Immediate and Early Loading of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants: 2-Year Results from a Prospective Clinical Study

“…By using resonance frequency analysis we were able to dispel this myth. 19 More than 85 dentists in 30 study sites participated, and an independent external review committee composed of experts internationally recognized in their respective fields closely monitored the study. This was equal or better that other immediate loading studies 2,3,4,5. It has been theorized by some researchers that the layer of apatite that forms of the implant surface during the early stages of osseointegration may (or may not) contain endogenous proteins and 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 serve as a matrix for osteogenic cell attachment and growth on the implant surface.…”

“…With this implant we found no significant loss of stability and were able to get a survival success rate of 97.9%. 19 The researchers concluded that HA coating might offer some clinical advantages up to 36 months over uncoated surfaces when placed in poor-quality bone, 22 smokers, 17 or when implants were mobile at the time of placement, 17 but cautioned that further prospective research was needed to verify these findings. 12 Because the biologic fixation of bone tissue to implant surfaces has been reported by some clinicians to be faster with a calcium phosphate coating than with uncoated titanium surfaces, 15,16 some clinicians have assumed that the bone healing process around the implant may be enhanced by the formation of the biological apatite layer, which may result in better early stability.…”

“…16,19 The HA coating was positioned 2.5 mm below the top and 3.3 mm above the bottom of the implant. The quantity and quality of available bone and the locations of vital anatomic structures were confirmed with cone beam computed tomography (CBCT).…”