Five-year changes in 24-hour sleep-wake activity and dementia risk in oldest old women
Sasha Milton,
Clémence Cavaillès,
Sonia Ancoli-Israel
et al.
Abstract:Introduction Sleep disruptions are associated with cognitive aging in older adults. However, it is unclear whether longitudinal changes in 24-hour multidimensional sleep-wake activity are linked to cognitive impairment in the oldest old. Methods We studied 733 cognitively unimpaired women (mean (standard deviation) age=82.5 (2.9) years) who completed two actigraphy assessments over five years. We performed hierarchical clustering on principal components in nine sleep, napping, and circadian rest-activity rhyth… Show more
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