To study the relative and absolute timing of post-Variscan cooling and denudation processes in the Erzgebirge of the Mid-European Variscides, eight samples for apatite fission-track (AFT) analysis were collected from a~1,300 m drill-core. The fission-track data reveal two stages of accelerated cooling through the apatite partial annealing zone (APAZ; i.e., 110€10-60 C) in the Late Jurassic-Late Cretaceous and in the late Cenozoic, respectively. Late Jurassic-Late Cretaceous cooling corresponding to denudation of 1.5-5.9 km has been related to wrench tectonics along the Elbe Zone during Triassic-Jurassic Pangea breakup. Late Cenozoic exhumation of 2.1-5.6 km, and the increase of the geothermal gradient from 17€5 C km 1 (Oligocene/ Miocene) to 25-27 C km 1 (recent) is likely connected to the formation of the Eger Graben starting from the Oligocene, as a result of the late Alpine orogenic phases.