Fischeria A, a novel norditerpene lactone from Euphorbia fischeriana

Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana

“…13 C-NMR (125 MHz) 168.1 (C-16), 151.0 (C-13), 132.9 (C-15), 85.4 (C-12), 66.7 (C-8), 61.5 (C-11), 56.5 (C-17), 55.2 (C-14), 53.5 (C-5), 47.8 (C-9), 41.2 (C-3), 39.2 (C-10), 39.1 (C-1), 35.6 (C-7), 33.5 (C-4), 33.4 (C-18), 21.8 (C-19), 20.8 (C-6), 18.4 (C-2), 15.5 (C-20). The 1 H- and 13 C-NMR data were in agreement with the reported data [ 9 , 22 , 30 ].…”

“…Due to the fact that it is a common Chinese herb used in medicane, the chemical constituents and bioactivities of E. fischeriana roots have been extensively studied and the known chemical constituents of this medicinal herb include monoterpenoids, flavonoids, anthraquinones, tannins, cerebrosides, glycerols, phenolics, diterpenoids, triterpenoids and steroids [ 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ]. A number of abietane diterpenoids, including jolkinolide A and B, and 17-hydroxyjolkinolide A and B were isolated.…”

The extraction process optimization and physicochemical properties of polysaccharides from the roots of Euphorbia fischeriana

“…Until now there are almost 60 constituents isolated and identified from the roots of E. fischeriana, such as diterpenoids, triterpenoids, steroids, tannins and so on. Most of them have been confirmed to be diterpenoids, which include the abietane-type lactones (jolkinolides) and tigliane-type derivatives [4][5][6]. Some of these diterpenoids exhibited significant antitumor activity against several tumor lines, such as sarcoma 180, Ehrlich ascites carcinoma and hepatocellar carcinoma in mice [7,8].…”

ent-Abietane and Tigliane Diterpenoids from the Roots of Euphorbia fischeriana and Their Inhibitory Effects against Mycobacterium smegmatis

“…On comparison of their physical and spectroscopic data with published values, the known compounds were identified as the ent-abietane-type and tigliane-type diterpenoids 7β,11β,12βtrihydroxy-ent-abieta-8( 14),13(15)-dien-16,12-olide (5), 10 langduin B (6), 15 (4R,4aR)-dihydroxy-3-hydroxymethyl-7,7,10at r i m e t h y l -2 , 4 , 4 a , 5 , 6 , 6 a , 7 , 8 , 9 , 1 0 , 1 0 a , l 0 bdodecahydrophenanthro [3,2-b]furan-2-one (7), 33 yuexiandajisu E (8), 29 jolkinolide A ( 9), 15 17-hydroxyjolkinolide A (10), 15 jolkinolide B (11), 15 17-hydroxyjolkinolide B ( 12), 15 fischeroside A ( 17), 22 phorbol-13-acetate ( 18), 17 12-deoxyphorbol-13acetate (prostratin) (19), 34 12-deoxyphorbaldehyde-13-acetate (20), 12 and langduin A (21). 8 The MIC values of the isolated compounds against M. smegmatis were evaluated, and the results are shown in Table 3.…”

“…fischeriana have revealed the presence of polysaccharides, − diterpenoids, triterpenoids, steroids, and acetophenone derivatives . Among these, the major chemical constituents of this plant are diterpenoids, including compounds of the abietane, tigliane, tigliane glycoside, and pimarane types, as well as dimeric diterpenoids, and norditerpenoids. − Some of these substance have displayed biological activities, including antibacterial, antituberculosis, anti-inflammatory, and cytotoxic effects. − …”