First-Trimester Sonographic Evaluation of Palatine Clefts: A Novel Diagnostic Approach

Lakshmy, S.; Deepa, S.; Rose, Nicholas E.; Mookan, Senthilkumar; Agnees, Joy

doi:10.7863/ultra.16.05084

Cited by 27 publications

(36 citation statements)

References 33 publications

(53 reference statements)

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“…The retronasal triangle does not serve to identify isolated cleft of secondary palate and clefts confined to the premaxilla alone 10 . We were able to achieve a high detection rate of palatine clefts in first trimester by using a combination of all three planes namely the sagittal, axial and coronal views in our study 35 .…”

Section: Rotten Et Al In 2004 Observed That the Presence Of Midline Ementioning

confidence: 79%

“…The retronasal triangle has been proposed as a sonographic landmark for first-trimester screening for cleft palate, but it does not serve to identify isolated cleft of the secondary palate and clefts confined to the premaxilla alone 10 . In a recent study 35 , we were able to achieve a high detection rate of palatine clefts in the first trimester by using a combination of all three planes, i.e. sagittal, axial and coronal views.…”

Section: Discussionmentioning

confidence: 99%

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Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Lakshmy

Rose

Masilamani

et al. 2020

Ultrasound in Obstet & Gyne

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What are the novel findings of this work? We describe a new sonographic sign, the 'superimposedline' sign, for evaluation of the fetal secondary palate in early gestation on two-dimensional imaging of the vomeromaxillary junction in the midsagittal view. What are the clinical implications of this work? Inclusion of this sign during the routine nuchal translucency scan should improve screening and early detection of secondary palatine clefts. This sign also facilitates evaluation of cleft extension into the secondary palate when a defect in the premaxilla is identified.

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Section: Rotten Et Al In 2004 Observed That the Presence Of Midline Ementioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Lakshmy

Rose

Masilamani

et al. 2020

Ultrasound in Obstet & Gyne

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show abstract

“…Although 2D axial, sagittal, and coronal views are complementary to one another in detecting cleft palate, a further 3D evaluation would be necessary. [ 12 ] Faure et al . conducted a study on 2D and 3D ultrasound scans on cleft palate, which found the adjusted kappa coefficient between prenatal and postnatal findings to be 0.88 which corresponds to an excellent agreement.…”

Section: R Esultsmentioning

confidence: 99%

Accuracy of prenatal ultrasound scans for screening cleft lip and palate: A systematic review

Divya

Raghavan

et al. 2022

J Med Ultrasound

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Children born with clefts encounter various postnatal issues which have a negative impact and long-term psychological effects on both the parents and themselves. This systematic review aims to find the accuracy of two-dimensional (2D)/3D scans for screening cleft lip and palate which would help the parents to be mentally and psychologically prepared to plan for future surgeries. To identify relevant literature, an electronic search was performed using PubMed, Trip database, Cochrane, and Google Scholar database. The search yielded 927 articles, of which 10 fulfilled the eligibility criteria and were included in this systematic review. These studies showed that the combination of 2D and 3D ultrasound scans has increased the specificity and sensitivity in detecting orofacial clefts, as they aid in improved visualization of the fetal face. However, in future, the visualization of the palate can be improved by inventing other modified views as cleft palate diagnosis is more prone to error.

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“…Harmonic imaging, compound imaging, and speckle reduction may be beneficial in enhancing visualization of fetal anatomy. Three‐dimensional postprocessing may be helpful in certain clinical situations 122,123 …”

Section: Equipment Specificationsmentioning

confidence: 99%

AIUM Practice Parameter for the Performance of Detailed Diagnostic Obstetric Ultrasound Examinations Between 12 Weeks 0 Days and 13 Weeks 6 Days

2020

J of Ultrasound Medicine

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This practice parameter is intended to provide the medical ultrasound community with recommendations for the performance and recording of high-quality ultrasound examinations. The parameter reflects what the AIUM considers the appropriate criteria for this type of ultrasound examination but is not intended to establish a legal standard of care. Examinations performed in this specialty area are expected to follow the parameter with recognition that deviations may occur depending on the clinical situation.This specialized diagnostic examination is an extension of the standard sonographic fetal assessment described in the AIUM-ACR-ACOG-SMFM-SRU Practice Parameter for the Performance of Standard Diagnostic Obstetric Ultrasound Examinations and the American College of Obstetricians and Gynecologist practice bulletin Ultrasound in Pregnancy. 1,2 The detailed obstetric ultrasound examination in the late first trimester is an indication-driven examination for women at increased risk for fetal or placental abnormalities that are potentially detectable between 12 weeks 0 days and 13 weeks 6 days' gestation. Performance and interpretation of this examination require advanced training, knowledge, and imaging

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First-Trimester Sonographic Evaluation of Palatine Clefts: A Novel Diagnostic Approach

Abstract: The study demonstrates that evaluation of the palate can be done at the 11 to 14 week scan based on 2D markers and can also be assessed with 3D sonography. The inclusion of 2D markers in all 3 planes increases the sensitivity for detection of palatine clefts.

Cited by 27 publications

References 33 publications

Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Accuracy of prenatal ultrasound scans for screening cleft lip and palate: A systematic review

AIUM Practice Parameter for the Performance of Detailed Diagnostic Obstetric Ultrasound Examinations Between 12 Weeks 0 Days and 13 Weeks 6 Days

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