First trimester screening for preterm and term pre‐eclampsia by maternal characteristics and biophysical markers in a low‐risk population

Sepúlveda‐Martínez, A.; Rencoret, G.; Silva, María C.; Ahumada, Paz; Pedraza, D.; Muñoz, H.; Valdés, Elena; Parra-Cordero, Mauro

doi:10.1111/jog.13809

Cited by 10 publications

(4 citation statements)

References 22 publications

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“…Many epidemiologic studies have taken on the challenge of identifying potential risk factors and predicting biomarkers for HDP; however, the prevention of HDP has not yet been elucidated 33 . Our findings may provide a rationale for developing new strategies to regulate uterine function and prevent HDP.…”

Section: Discussionmentioning

confidence: 83%

Hypertensive disorders of pregnancy are associated with dysmenorrhea in early adulthood: A cohort study

Nakayama

Ono

Iizuka

et al. 2020

J of Obstet and Gynaecol

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Aim: Hypertensive disorders of pregnancy (HDP) are serious conditions that occur in 5-10% of pregnancies. Maternal factors, such as maternal age, obesity, and renal disease, have been described as risk factors. In order to extract the background lifestyle and gynecological characteristics for HDP, we conducted a prospective cohort study. Methods: Pregnant participants were administered a questionnaire on characteristics, menstrual abnormalities and lifestyle factors. The women were followed individually until 1-month postpartum. We used medical records to examine the relationship between menstrual abnormalities and the onset of HDP. Results: We collected data from 193 pregnant women, and excluding 3 who had miscarriage, examined the records of 190. A total of 26 patients developed HDP, of which 10 had early-onset HDP and 16 had late-onset HDP. Although there was no significant association between HDP and dysmenorrhea just prior to pregnancy, there was a significant increase in the incidence of HDP in patients who experienced dysmenorrhea around the age of 20 years (odds ratio 4.362 [95% CI 1.61-11.81]). Conclusion: We found that patients with a history of dysmenorrhea around the age of 20 years have a significantly higher risk of developing HDP. Although dysmenorrhea in young adulthood is ameliorated, it may become apparent as a perinatal disease when a physical load such as pregnancy is applied.

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Section: Discussionmentioning

confidence: 83%

Hypertensive disorders of pregnancy are associated with dysmenorrhea in early adulthood: A cohort study

Nakayama

Ono

Iizuka

et al. 2020

J of Obstet and Gynaecol

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“…Pulsed wave Doppler is performed and the UtA-PI and peak systolic velocity are measured when three similar consecutive waveforms are obtained. A study evaluating low-risk Latin-American women in the first trimester of pregnancy found that the detection rate for preterm preeclampsia was 62.1% (AUC 0.817) based on maternal characteristics, which increased to 72.4% (AUC 0.890) with the inclusion of MAP and uterine artery Doppler measurements [66]. Antwi and colleagues found that predictive ability for gestational hypertension in Ghanaian women improved with the incorporation PAPP-A and PIGF measurements between 8 to 13 weeks of gestation [67].…”

Section: Biomarkers and Biophysical Factors In Pe Developmentmentioning

confidence: 99%

Optimising Cardiometabolic Risk Factors in Pregnancy: A Review of Risk Prediction Models Targeting Gestational Diabetes and Hypertensive Disorders

Thong

Ghelani

Manoleehakul

et al. 2022

JCDD

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Cardiovascular disease, especially coronary heart disease and cerebrovascular disease, is a leading cause of mortality and morbidity in women globally. The development of cardiometabolic conditions in pregnancy, such as gestational diabetes mellitus and hypertensive disorders of pregnancy, portend an increased risk of future cardiovascular disease in women. Pregnancy therefore represents a unique opportunity to detect and manage risk factors, prior to the development of cardiovascular sequelae. Risk prediction models for gestational diabetes mellitus and hypertensive disorders of pregnancy can help identify at-risk women in early pregnancy, allowing timely intervention to mitigate both short- and long-term adverse outcomes. In this narrative review, we outline the shared pathophysiological pathways for gestational diabetes mellitus and hypertensive disorders of pregnancy, summarise contemporary risk prediction models and candidate predictors for these conditions, and discuss the utility of these models in clinical application.

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“…Es interesante que la mayoría de los síndromes obstétricos tienen una larga fase subclínica y sus expresiones clínicas son manifestaciones tardías de los procesos fisiopatológicos que los ocasionan 5 . Por ejemplo, la infección intraamniótica 7,8 y el acortamiento cervical [9][10][11] pueden ser asintomáticos y asociarse con un resultado adverso perinatal semanas después; igualmente, las alteraciones del Doppler de las arterias uterinas [12][13][14] y los cambios en las concentraciones de factores angiogénicos y antiangiogénicos [15][16][17] preceden en semanas al desarrollo de un cuadro de preeclampsia o de restricción del crecimiento fetal.…”

Section: Revista Chilena Deunclassified

Predicción de los grandes síndromes obstétricos

Kusanovic¹

2021

RECHOG

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First trimester screening for preterm and term pre‐eclampsia by maternal characteristics and biophysical markers in a low‐risk population

Abstract: Preterm PE can be predicted by a combination of maternal characteristics and biophysical markers. However, first trimester screening is less valuable for term PE.

Cited by 10 publications

References 22 publications

Hypertensive disorders of pregnancy are associated with dysmenorrhea in early adulthood: A cohort study

Hypertensive disorders of pregnancy are associated with dysmenorrhea in early adulthood: A cohort study

Optimising Cardiometabolic Risk Factors in Pregnancy: A Review of Risk Prediction Models Targeting Gestational Diabetes and Hypertensive Disorders

Predicción de los grandes síndromes obstétricos

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