First trimester prenatal diagnosis of a severe tricuspid valve regurgitation and pulmonary valve atresia

Abstract

Early diagnosis of congenital heart defect (CHD) increased in the last two decades, following technological evolution. A recent meta‐analysis (Yu, 2020), on diagnostic accuracy in ultrasound detection of major CHD in the first trimester of pregnancy, reported an overall sensitivity of 75%. Ultrasound imaging of this case refers to a tricuspid valve dysplasia with right atriomegaly and pulmonary valve atresia diagnosed in a 13‐week gestational‐age fetus with low risk for chromosomal abnormalities. To our knowledge, this is the first case describing such features in the first trimester. We believe the precocity and severity of onset make this a case of diagnostic interest.

A case report of pulmonary atresia with intact ventricular septum: an extraordinary finding of subsystemic right ventricle

“…Fetal studies have implied that the outcomes after decompression of RV in infants with PA/IVS are associated with the degree of the TR ( 7 ). The absence or presence of mild baseline TR is a contributing factor to not reaching the desired BV circulation outcome ( 8 ). Lacobelli et al demonstrated that the absence of TR in fetal PA/IVS correlated to single ventricle circulation postnatally in addition to ventriculocoronary connections ( 9 ).…”