It has been found that while the highly nonuniform direct current Lreakdown voltages, V , o£ H2 and NH3 exceed, respectively, those of B? and ND3, the Vs of CHi, is substantially lower than that of CDi,. The former (direct) isotope effect may be attributed to the higher ionization coefficients for the deuterated species compared with the nondeuterated, and the latter (inverse) isotope elfact may result from differences in the electron-impact-induced dissociation processes of the isotopic pairs of molecules.We have measured the direct current (DC) breakdown