First Row Transition Metal Mediated Redox Reactions of Hydrazines and Isonitriles

Abstract

Over the past 50 years, there has been an explosion in the progress of transition-metal mediated reaction design, allowing chemists to perform a vast array of organic and inorganic transformations. While first-row transition-metals play a role in many reactions that have been known for some time, second-and third-row transition-metals have been key for the discovery and success of many of the most well-known and utilized reactions in homogeneous catalysis existing today. However, developing reactions utilizing first-row transition-metals has regained in popularity over recent years, in part due to the general expense of heavier metals. Also, the ability of first-row transition-metals to perform unique transformations or tolerate different functional groups in substrates is often a motivation to explore their applications in synthetic reactions.