First reported case of ganglioneuroblastoma in pregnancy and a review of the literature

Chen, Bee Fong; Rathi, Manjusha; Al-Samarrai, S; Rajeswary, Jyothi

doi:10.1177/1753495x14533534

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…[ 2 ] It has been reported that ganglioneuroblastoma is seen most commonly during early childhood, especially in children under the age of 5 years with equal occurrence in males and females. [ 4 , 5 ]…”

Section: Discussionmentioning

confidence: 99%

Primary cervical ganglioneuroblastoma

et al. 2018

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Rationale:Ganglioneuroblastoma is usually located in the adrenal gland, retroperitoneal ganglia, or posterior mediastinum, but rarely occurs in the parapharyngeal space.Patient concerns:A 4-year-old girl presented with complaint of progressive inspiratory dyspnea and dysphagia, accompanying left-side Horner's syndrome.Diagnose:Computed tomography (CT) scan revealed a giant mass with irregular low density in left oropharyngeal and posterior pharyngeal wall. The left carotid artery sheath was pushed to the right. After enhancement, the central part of the mass was strengthened, and the surrounding bones structures appeard normal. Magnetic resonance imaging (MRI) showed a solid mass in the left parapharyngeal space displacing the left carotid sheath posteriorly and laterally. A ganglioneuroblastoma was diagnosed.Intervations:The girl was treated by surgery.Outcomes:The postoperative course was uneventful. There was no recurrence was observed during the 1-year follow-up.Lessons:The primary cervical ganglioneuroblastoma is rare, we recommended the ganglioneuroblastoma should be considered in the differential diagnosis of a child presenting with a parapharyngeal space mass.

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Section: Discussionmentioning

confidence: 99%

Primary cervical ganglioneuroblastoma

et al. 2018

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“…Ganglioneuroblastomas are extremely rare in adults, with only about 50 cases documented in people over the age of 20, and only five cases observed in the adult brain [7]. According to the present authors' knowledge, there are no reports in the literature of ganglioneuroblastoma presenting during pregnancy [8].…”

Section: Discussionmentioning

confidence: 66%

Ganglioneuroblastoma during pregnancy – A rare case report

Moga¹,

Daniilidis²,

Bigiu³

et al. 2016

Clin. Exp. Obstet. Gynecol.

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To report a rare case of ganglioneuroblastoma encountered rarely in adults, especially during pregnancy. Materials and Methods: The authors present a case of ganglioneuroblastoma relapse during the third trimester of pregnancy in a patient previously treated for ganglioneuroblastoma who had a eight-year disease-free interval. Late manifestation of neurological symptoms (vestibular syndrome, nystagmus, slightly right motor deficit) was perhaps influenced by the hormonal pregnancy effects. In this case the option was for caesarean section under general anesthesia at 36 weeks. Results: Based on MRI result, the neurosurgical consultation stated the need of postpartum brain tumor excision. Recovery of the mother was complication-free with persistent, constant postoperative neurological symptoms. It resulted in a healthy newborn, not requiring special follow-up. Conclusions: Pregnancy and brain tumor have mutual negative effect on the patient. Therapeutic management in this case was a medical dilemma regarding mode setting and timing of delivery, taking into account the maternal-fetal risk-benefit.

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“…When diagnosing GNB, its clinical presentations are generally non-specific. Among the 104 reported cases, symptoms predominantly arose from compression by the primary or metastatic lesions ( 8 , 35 , 47 , 60 , 62 , 65 ). Some GNB cases with endocrine activity presented with endocrine-related symptoms such as diarrhea and malaise ( 4 , 15 , 36 , 49 , 77 ).…”

Section: Discussionmentioning

confidence: 99%

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature

Zhang,

Peng

et al. 2024

Oncol Lett

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Ganglioneuroblastoma (GNB), predominantly observed in children, is an uncommon malignant tumor in adults, with established treatment protocols notably lacking. The present study details the case of a 20-year-old woman who presented with a left adrenal gland mass, identified during a physical examination. Additionally, an unidentified mass was noted near the renal hilum in the preoperative evaluation. Following thorough preoperative preparation, both the primary adrenal gland mass and the renal hilar mass were surgically removed. The procedure concluded successfully. Pathological analysis confirmed that the left adrenal mass was a GNB and identified the renal hilar mass as a metastatic extension. Postoperative examination revealed a new formation at the original surgical site, later verified as a postoperative scar. Through the publication of a case report and extensive literature review, the present study aims to enhance our understanding of this condition, providing valuable diagnostic, therapeutic and post-recovery references for this rare adult disease.

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First reported case of ganglioneuroblastoma in pregnancy and a review of the literature

Cited by 5 publications

References 8 publications

Primary cervical ganglioneuroblastoma

Primary cervical ganglioneuroblastoma

Ganglioneuroblastoma during pregnancy – A rare case report

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature

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