First report of naturally infected Aedes aegypti with chikungunya virus genotype ECSA in the Americas

Costa-da-Silva, André Luis; Ioshino, Rafaella Sayuri; Petersen, Vivian; Lima, Antonio Fernando; Cunha, Marielton dos Passos; Wiley, Michael R.; Ladner, Jason T.; Prieto, Karla; Palacios, Gustavo; Costa, Danuza Duarte; Suesdek, Lincoln; Zanotto, Paolo Marinho de Andrade; Capurro, Margareth Lara

doi:10.1371/journal.pntd.0005630

Cited by 62 publications

(56 citation statements)

References 39 publications

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“…The same genotype was detected in Ae. aegypti collected in Sergipe and represented the first report in Brazil and in the Americas [87], and in human samples from Alagoas, Bahia, Paraíba, and Sergipe [88][89][90].…”

Section: Discussionmentioning

confidence: 94%

Natural Infection of Aedes aegypti by Chikungunya and Dengue type 2 Virus in a Transition Area of North-Northeast Brazil

Aragão

Pinheiro

Neto

et al. 2019

Viruses

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Dengue fever, chikungunya, and Zika are diseases caused by viruses transmitted by Aedes aegypti and Aedes albopictus. In Brazil, the number of human infections is high, but few studies are performed in mosquito vectors. This study aimed to investigate the presence of Zika, Dengue and Chikungunya viruses in Ae. aegypti and Ae. albopictus from the municipalities of Alto Alegre, Caxias, Codó, and São Mateus do Maranhão, located in the state of Maranhão, Northeast Brazil. The mosquitoes were collected with a mechanical aspirator, identified, triturated, and then submitted to RNA extraction and RT-qPCR. The positive samples were confirmed by virus isolation and genome sequencing. Three hundred and forty-eight Ae. aegypti (176 males and 172 females) and 12 Ae. albopictus (eight males and four females) were collected and tested. Ae. aegypti was the only vector positive in two municipalities—Codó, with detection of Chikungunya virus (CHIKV) belonging to the East-Central-South African genotype, and in Caxias, with detection of Dengue virus (DENV)-2 belonging to the Asian/American genotype. The detection of CHIKV and DENV-2 is evidence that those viruses are maintained in arthropod vectors, and shows the epidemiological risk in the area for chikungunya cases and a possible increase of severe dengue cases, associated with the occurrence of dengue hemorrhagic fever.

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Section: Discussionmentioning

confidence: 94%

Natural Infection of Aedes aegypti by Chikungunya and Dengue type 2 Virus in a Transition Area of North-Northeast Brazil

Aragão

Pinheiro

Neto

et al. 2019

Viruses

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“…More recently, with the first isolation in Brazil of the Chikungunya virus (CHIKV) in September, 2014, in the city of Oiapoque ‐ Amapá (Teixeira et al ) and of the Zika virus (ZIKV) in 2015 in the city of Camaçari – Bahia (Campos et al ), Ae. aegypti received still greater notoriety, as it was once again indicated as the principal vector of these etiological agents to human beings, naturally infected specimens already having been found (Ferreira‐de‐Brito et al , Costa‐da‐Silva et al ).…”

Section: Introductionmentioning

confidence: 99%

Parity and gonotrophic discordance of females ofAedes aegyptiandAedes albopictus(Diptera: Culicidae) in the city of São Paulo, SP, Brazil

Andrade

Urbinatti

Coelho

et al. 2019

Journal of Vector Ecology

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The objective of this study was to assess the parity, presence of blood in the stomach, and the gonotrophic discordance of females of Aedes aegypti and Aedes albopictus captured in two areas of the city of São Paulo. The captures were undertaken monthly, by aspiration, in the period from January, 2015 to August, 2017. All the females of the two species had their midguts and ovaries dissected to determine the presence of blood and the parity/stage of maturation. With regard to parity, 27% and 34% of the females of Ae. aegypti and Ae. albopictus, respectively, were parous or were in advanced stages of the development of their ovaries (33% and 27%, respectively). The larger part of the females of Ae. aegypti and Ae. albopictus contained blood in their stomachs (77% and 60%, respectively), beyond which 36% and 27% of the females of Ae. aegypti and Ae. albopictus, respectively, were in gonotrophic discordance. Our results indicate favorable conditions in the study areas because of the presence of parous females. Moreover, this frequent and multiple contact of Ae. aegypti and Ae. albopictus females with vertebrate hosts, such as humans, increases the possibility of transmitting the viruses they may be carrying.

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“…Although CHIKV ECSA has been found only in Ae. aegypti mosquitoes ( 9 ), a recent study has shown that Ae. albopictus mosquitoes in Brazil are also highly competent in CHIKV ECSA transmission ( 10 ).…”

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confidence: 99%

Spread of Chikungunya Virus East/Central/South African Genotype in Northeast Brazil

Costa¹,

Thézé²,

Komninakis³

et al. 2017

Emerg. Infect. Dis.

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First report of naturally infected Aedes aegypti with chikungunya virus genotype ECSA in the Americas

Abstract: Background

Cited by 62 publications

References 39 publications

Natural Infection of Aedes aegypti by Chikungunya and Dengue type 2 Virus in a Transition Area of North-Northeast Brazil

Natural Infection of Aedes aegypti by Chikungunya and Dengue type 2 Virus in a Transition Area of North-Northeast Brazil

Parity and gonotrophic discordance of females ofAedes aegyptiandAedes albopictus(Diptera: Culicidae) in the city of São Paulo, SP, Brazil

Spread of Chikungunya Virus East/Central/South African Genotype in Northeast Brazil

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