First report of Karimabad virus in Rhombomys opimus in China

Li, Yue; Wang, Yuna; Tian, Feng; Zhang, Xiaolong; Zhang, Jingtao; Li, Shuang; Li, Hao; Zhang, Xiao-Ai; Liu, Wei

doi:10.1016/j.onehlt.2022.100437

Cited by 3 publications

(3 citation statements)

References 15 publications

(25 reference statements)

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“…Sandfly fever was also diagnosed in military personnel in Afghanistan in 2017 [32]. The spread of SBVs is a public health concern in several parts of the world, with a more recent example of KARVs being identified in gerbils in China [33]. Therefore, future investigations on SBVs are needed to elucidate the role of SBVs, sandflies, and potential alternate reservoirs of SBVs in countries such as Iran, as many unknowns still exist.…”

Section: Discussionmentioning

confidence: 99%

Genetic Characterization of Sandfly-Borne Viruses in Phlebotomine Sandflies in Iran

Shahhosseini,

Paquette,

Kayedi

et al. 2023

Microorganisms

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Phleboviruses are classified into two main groups: the sandfly fever group (transmitted by sandflies and mosquitoes) and the Uukuniemi group (transmitted by ticks). Old World sandfly-borne viruses (SBVs) are classified into four main serocomplexes; sandfly fever Naples viruses (SFNVs), sandfly fever Sicilian viruses (SFSVs), Karimabad viruses (KARVs), and Salehabad viruses (SALVs). This study addresses current knowledge gaps on SBVs in Iran by focusing on identification and molecular epidemiology. We used PCR to examine DNA/RNA extracts to identify sandfly species and evaluate for SBV presence. We identified five specimens positive for phleboviruses: one Ph. sergenti for Tehran virus (TEHV), one Ph. papatasi for SFSV, and two Ph. papatasi and one Ph. perfiliewi for KARV. A phylogenetic tree indicated that the TEHV isolate from this study formed a cluster with previous isolates of TEHV, Zerdali virus, and Fermo virus. Meanwhile, the identified SFSV isolate fell in lineage I and was grouped with previous isolates of SFSVs and Dashli virus in Iran. Finally, the KARV isolates from this study formed a monophyletic clade in a sister relationship with other viruses in KARV lineages I and II. This comprehensive study on SBVs in Iran provided new insights into the molecular epidemiology of TEHV, SFSVs and KARVs in this country.

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Section: Discussionmentioning

confidence: 99%

Genetic Characterization of Sandfly-Borne Viruses in Phlebotomine Sandflies in Iran

Shahhosseini,

Paquette,

Kayedi

et al. 2023

Microorganisms

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“…Meanwhile, > 100 animal species, including red fox ( Vulpes vulpes ), marble polecat ( Vormela peregusna ), long-eared hedgehog ( Hemiechinus auritus ) and goitered gazelle ( Gazella subgutturosa sairensis ) live in the area [ 4 ]. The great gerbil, the most dominant rodent species in the Gurbantunggut Desert, was previously reported to carry a variety of tick-borne pathogens, such as Tacheng tick virus 1, Songling virus [ 5 ], Karimabad virus [ 6 ], Babesia spp., Theileria spp. and Anaplasma ovis [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

The great gerbil (Rhombomys opimus) as a host for tick species in Gurbantunggut Desert

Liu,

Tan,

Wang

et al. 2024

Parasites Vectors

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Background Rodents play an important role in the life cycle of ixodid and argasid ticks, particularly as hosts of larvae and nymphs. The great gerbil (Rhombomys opimus), the preferred prey item of several carnivores (e.g. the red fox and marbled polecat), is the dominant rodent species in the Gurbantunggut Desert in northwestern China. The aim of this study was to investigate tick species associated with different hosts in the habitat of great gerbils, including wildlife and livestock. Methods During 2018–2023, ticks were removed from 326 great gerbils, two red foxes (Vulpes vulpes), three marbled polecats (Vormela peregusna), 35 pastured sheep (Ovis aries), and one long-eared desert hedgehog (Hemiechinus auritus) in the Gurbantunggut Desert. Ticks were identified according to standard morphological keys. Then, they were further analyzed by molecular and phylogenic methods based on two mitochondrial markers, 16S rDNA and cytochrome c oxidase subunit I (COI) genes. Results A total of 889 ticks were collected, representing five species. These included Hyalomma asiaticum (n = 425: 24 larvae, 79 nymphs and 322 adults), Rhipicephalus turanicus (n = 153: 2 nymphs and 151 adults), Haemaphysalis erinacei (n = 298: 4 larvae, 7 nymphs and 287 adults), Ixodes acuminatus (n = 7: 4 nymphs and 3 adults) and Ornithodoros tartakovskyi (6 adults). Based on COI sequences, molecular and phylogenetic analyses showed that (i) I. acuminatus from great gerbils and marbled polecats clustered with I. acuminatus reported from Europe; (ii) O. tartakovskyi found in northwestern China belonged to an independent clade; (iii) Hy. asiaticum, R. turanicus and Ha. erinacei had 100% sequence identities to conspecific ticks sampled previously in China. Conclusions The great gerbil is an important host for the developmental stages of I. acuminatus, O. tartakovskyi, Ha. erinacei, Hy. asiaticum and R. turanicus, thus supporting the life cycle of several tick species which, as adults, parasitize predators (red fox and marble polecat) as well as pastured sheep and hedgehogs in the Gurbantunggut Desert. Ixodes acuminatus and O. tartakovskyi were found for the first time on great gerbil and marbled polecat, respectively. Graphical Abstract

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“…The local ora consists mainly of sand-xing shrubs including Haloxylon ammodendron, Haloxylon persicum and Calligonum mongolicum [2]. As the dominant rodent species in the Gurbantunggut Desert, the great gerbil (Rhombomys opimus) was previously reported to carry a variety of tick-borne pathogens, such as Tacheng Tick Virus 1, Songling Virus [3], Karimabad virus [4], Babesia spp., Theileria spp. and Anaplasma ovis [5].…”

mentioning

confidence: 99%

The great gerbil (Rhombomys opimus) as a host for tick species in Gurbantunggut desert

Liu,

Tan,

Han

et al. 2023

Preprint

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Background Rodents play an important role in the life cycle of ixodid and argasid ticks, particularly as hosts of larvae and nymphs. The great gerbil (Rhombomys opimus), the preferred prey item of several carnivores (e.g., the red fox and the marbled polecat), is the dominant rodent species in the Gurbantunggut Desert, in northwestern China. The aim of this study was to investigate tick species associated with different hosts in the habitat of great gerbils, including wildlife and livestock. Methods During 2018–2023, ticks were removed from 326 great gerbils (Rhombomys opimus), two red foxes (Vulpes vulpes), three marbled polecats (Vormela peregusna), 35 pastured sheep (Ovis aries), and one long-eared desert hedgehog (Hemiechinus auritus) in the Gurbantunggut Desert. Ticks were identified according to standard morphological keys. Then they were further analyzed by molecular and phylogenic methods based on two mitochondrial markers, the 16S rDNA and the cytochrome c oxidase subunit I (COI) genes. Results A total of 889 ticks were collected, representing five species. These included Hyalomma asiaticum (n = 425: 24 larvae, 79 nymphs and 322 adults), Rhipicephalus turanicus (n = 153: 2 nymphs and 151 adults), Haemaphysalis erinacei (n = 298: 4 larvae, 7 nymphs and 287 adults), Ixodes acuminatus (n = 7: 4 nymphs and 3 adults) and Ornithodoros tartakovskyi (6 adults). Based on COI sequences, molecular and phylogenetic analyses showed that i) I. acuminatus from great gerbils and marbled polecats clustered with I. acuminatus reported from Europe; ii) O. tartakovskyi found in northwestern China belonged to an independent clade; and iii) Hy. asiaticum, R. turanicus and Ha. erinacei had 100% sequence identities to conspecific ticks sampled previously in China. Conclusions The great gerbil is an important host for the developmental stages of I. acuminatus, O. tartakovskyi, Ha. erinacei, Hy. asiaticum and R. turanicus, thus supporting the life cycle of several tick species which, as adults, parasitize predators (the red fox and the marble polecat), as well as pastured sheep and hedgehogs in the Gurbantunggut Desert. Ixodes acuminatus and O. tartakovskyi were found for the first time on great gerbil and marbled polecat, respectively.

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First report of Karimabad virus in Rhombomys opimus in China

Cited by 3 publications

References 15 publications

Genetic Characterization of Sandfly-Borne Viruses in Phlebotomine Sandflies in Iran

Genetic Characterization of Sandfly-Borne Viruses in Phlebotomine Sandflies in Iran

The great gerbil (Rhombomys opimus) as a host for tick species in Gurbantunggut Desert

The great gerbil (Rhombomys opimus) as a host for tick species in Gurbantunggut desert

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