First Report of <i>Colletotrichum truncatum</i> Causing Anthracnose of Mouse Garlic (<i>Allium angulosum</i>) in India

Salunkhe, Vanita Navnath; Anandhan, Sivalingam; Gawande, S. J.; Ikkar, R. B.; Bhagat, Yogesh; Mahajan, Vijay

doi:10.1094/pdis-04-17-0566-pdn

Cited by 6 publications

(2 citation statements)

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“…Wild (Bear) garlic ( A. ursinum L.) reveals similar taste and healing properties. Mouse garlic ( Allium angulosum L.) is important for its use as a spice, a vegetable and an ornamental plant in India (6). This area also includes Allium tibeticum Rendle which is the synonym of A. sikkimense Baker.…”

Section: Popular Scientific Summarymentioning

confidence: 99%

Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

Korga

Ostrowska

Iwan

et al. 2019

Food & Nutrition Research

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Background Gastric cancer (GC) remains one of the leading causes of cancer-related death. Its aetiology is multifactorial, but the major risk factor is a high in salt diet. During gastric carcinogenesis, cadherin-1 (CDH1) down-expression and cyclooxygenase 2 (COX2) overexpression may be observed. The intensity of these alterations contributes to the GC invasion, its metastases and poor prognosis. As the diet plays a significant role in the aetiology of GC, it is reasonable to include the nutritional chemoprevention agents. One of the plant genus demonstrating chemoprotective properties is Allium genus, which includes garlic. The relationship between CDH1 and COX2 in GC cells treated with Allium species extract has never been evaluated. Methods In this study, the MKN28 and MKN74 GC cell lines were treated with ethanol extracts of Allium angulosum L., Allium lusitanicum Lam., Allium sativum L. (from Malaysia and Poland), Allium tibeticum Rendle and Allium ursinum L. The cytotoxicity of the extracts and their influence on COX2 and CDH1 mRNA and protein expression were evaluated as well as their influence on doxorubicin’s (DOX) efficacy – a drug that has been used in GC treatment. Results Among the tested species, ethanol extracts of A. sativum L. (Poland and Malaysia), A. tibeticum Rendle and A. ursinum L. influenced the levels of CDH1 and COX2, but only in the MKN74 cell line. Thus, it is possible that tumours with increased COX2 expression will be more susceptible to garlic treatment. Observed phenomenon was independent of Allium extract’s toxicity. In comparison to DOX, tested extracts were more toxic. Moreover, A. sativum revealed synergistic effect with the drug. Conclusion In conclusion, the results indicate the potential application of Allium genus to GC chemoprevention and treatment support through CDH restoration and COX2 downregulation. This issue needs further investigations as it might be used in clinics.

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Section: Popular Scientific Summarymentioning

confidence: 99%

Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

Korga

Ostrowska

Iwan

et al. 2019

Food & Nutrition Research

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“…Several other Colletotrichum spp. such as C. circinans (Kim et al, 2008 ; Kiehr et al, 2012 ; Chen et al, 2022 ), C. coccodes (Rodriguez-Salamanca et al, 2012 ; Baysal-Gurel et al, 2014 ; Hay et al, 2016 ), C. siamense, C. truncatum (Chowdappa et al, 2015 ; Salunkhe et al, 2018a ), C. spaethianum (Santana et al, 2015 ; Salunkhe et al, 2018b ), and recently three members of C. acutatum species complex ( C. nymphaeae, C. scovillei , and C. tamarilloi ), and two members of C. gloeosporioides species complex ( C. fructicola, C. theobromicola ) (Lopes et al, 2021 ) have been reported in onion crop and their wild relatives. Thus, all earlier studies revealed that onion anthracnose is a disease complex predominantly caused by the Colletotrichum species complex and the association of G. moniliformis , which helps to increase symptom severity.…”

Section: Taxonomic and Molecular Characterization Of Collet...mentioning

confidence: 99%

Concurrent waterlogging and anthracnose-twister disease in rainy-season onions (Allium cepa): Impact and management

et al. 2022

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Waterlogging and anthracnose-twister disease are significant obstacles in rainy-season onion cultivation. As a shallow-rooted crop, onions are highly sensitive to waterlogging. Wherever rainy-season onion cultivation has been undertaken, the anthracnose-twister disease complex is also widespread across the world in addition to waterlogging. Waterlogging is the major predisposing factor for anthracnose and other fungal diseases. However, studies on the combined stress impact on onions have been ignored. In the present review, we have presented an overview of the anthracnose-twister disease, the waterlogging effect on host physiology, host-pathogen interaction under waterlogging stress, and appropriate management strategies to mitigate the combined stress effects. Crucial soil and crop management strategies can help cope with the negative impact of concurrent stresses. Raised bed planting with drip irrigation, the use of plant bio-regulators along with nutrient management, and need-based fungicide sprays would be the most reliable and feasible management options. The most comprehensive solution to withstand combined stress impacts would be a genetic improvement of commercial onion cultivars.

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Colletotrichum species and complexes: geographic distribution, host range and conservation status

2021

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First Report of Colletotrichum truncatum Causing Anthracnose of Mouse Garlic (Allium angulosum) in India

Cited by 6 publications

References 1 publication

Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

Concurrent waterlogging and anthracnose-twister disease in rainy-season onions (Allium cepa): Impact and management

Colletotrichum species and complexes: geographic distribution, host range and conservation status

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