First report of fingerprinting dried herbal products using a subtractive diversity array

Niu, Linhai; Mantri, Nitin; Wohlmuth, Hans; Li, Chun Guang; Xue, Charlie Changli; Pang, E. C. K.

doi:10.1515/jcim-2012-0002

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…ma-yuen Stapf), is a TCM widely recognized for its rich nutritional and medicinal value. Fingerprinting of Coicis semen from dried tissues using the sequence-independent microarray ( Niu et al, 2013 ) and the high-performance liquid chromatography (HPLC)-evaporative light scattering detector ( Du et al, 2021 ) has been reported. It contains more than 80 active components including polysaccharides, fatty acids (FAs), phenolic acids, sterols, lipids, flavonoids, triterpenes, alkaloids, and adenosine ( Zhu, 2017 ; Yu J. et al, 2022 ; Huang et al, 2022 ; Pan et al, 2023 ; Wei et al, 2023 ).…”

Section: The Cardiovascular Protective Activity Of Yyfzmentioning

confidence: 99%

Cardiovascular protection of YiyiFuzi powder and the potential mechanisms through modulating mitochondria-endoplasmic reticulum interactions

Ding,

Ji,

Wang

et al. 2024

Front. Pharmacol.

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Cardiovascular diseases (CVD) remain the leading cause of death worldwide and represent a major public health challenge. YiyiFuzi Powder (YYFZ), composed of Coicis semen and Fuzi, is a classical traditional Chinese medicine prescription from the Synopsis of Golden Chamber dating back to the Han Dynasty. Historically, YYFZ has been used to treat various CVD, rooted in Chinese therapeutic principles. Network pharmacology analysis indicated that YYFZ may exhibit direct or indirect effects on mitochondria-endoplasmic reticulum (ER) interactions. This review, focusing on the cardiovascular protective effects of Coicis semen and Fuzi, summarizes the potential mechanisms by which YYFZ acts on mitochondria and the ER. The underlying mechanisms are associated with regulating cardiovascular risk factors (such as blood lipids and glucose), impacting mitochondrial structure and function, modulating ER stress, inhibiting oxidative stress, suppressing inflammatory responses, regulating cellular apoptosis, and maintaining calcium ion balance. The involved pathways include, but were not limited to, upregulating the IGF-1/PI3K/AKT, cAMP/PKA, eNOS/NO/cGMP/SIRT1, SIRT1/PGC-1α, Klotho/SIRT1, OXPHOS/ATP, PPARα/PGC-1α/SIRT3, AMPK/JNK, PTEN/PI3K/AKT, β2-AR/PI3K/AKT, and modified Q cycle signaling pathways. Meanwhile, the MCU, NF-κB, and JAK/STAT signaling pathways were downregulated. The PERK/eIF2α/ATF4/CHOP, PERK/SREBP-1c/FAS, IRE1, PINK1-dependent mitophagy, and AMPK/mTOR signaling pathways were bidirectionally regulated. High-quality experimental studies are needed to further elucidate the underlying mechanisms of YYFZ in CVD treatment.

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Section: The Cardiovascular Protective Activity Of Yyfzmentioning

confidence: 99%

Cardiovascular protection of YiyiFuzi powder and the potential mechanisms through modulating mitochondria-endoplasmic reticulum interactions

Ding,

Ji,

Wang

et al. 2024

Front. Pharmacol.

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A guiding framework to understand relationships within the profession of massage therapy

Baskwill

2016

Journal of Bodywork and Movement Therapies

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First report of fingerprinting dried herbal products using a subtractive diversity array

Abstract: This technique provides a new way to produce markers for authenticating dried herbal samples.

Cited by 2 publications

References 26 publications

Cardiovascular protection of YiyiFuzi powder and the potential mechanisms through modulating mitochondria-endoplasmic reticulum interactions

Cardiovascular protection of YiyiFuzi powder and the potential mechanisms through modulating mitochondria-endoplasmic reticulum interactions

A guiding framework to understand relationships within the profession of massage therapy

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