First Report of Coronaviruses in Northern European Bats

Kivistö, Ilkka; Tidenberg, Eeva-Maria; Lilley, Thomas M.; Suominen, Kati; Forbes, Kristian M.; Vapalahti, Olli; Huovilainen, Anita; Sironen, Tarja

doi:10.1089/vbz.2018.2367

Cited by 24 publications

(24 citation statements)

References 12 publications

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“…Reports of coronaviruses in bats from the Nordic countries are limited. Previously, partial coronavirus ORF1b sequences from five different bat species in Denmark were reported [27] and, more recently, full-genome sequences of two separate coronaviruses-from Myotis daubentonii and Myotis brandtii-as well as other partial bat coronavirus (BtCoV) sequences, have been determined [28]. Still missing are full-genome sequences of coronaviruses from other bat species in the Nordic countries.…”

Section: Introductionmentioning

confidence: 99%

Full-Genome Sequences of Alphacoronaviruses and Astroviruses from Myotis and Pipistrelle Bats in Denmark

Lazov

Belsham

Bøtner

et al. 2021

Viruses

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Bat species worldwide are receiving increased attention for the discovery of emerging viruses, cross-species transmission, and zoonoses, as well as for characterizing virus infections specific to bats. In a previous study, we investigated the presence of coronaviruses in faecal samples from bats at different locations in Denmark, and made phylogenies based on short, partial ORF1b sequences. In this study, selected samples containing bat coronaviruses from three different bat species were analysed, using a non-targeted approach of next-generation sequencing. From the resulting metagenomics data, we assembled full-genome sequences of seven distinct alphacoronaviruses, three astroviruses, and a polyomavirus, as well as partial genome sequences of rotavirus H and caliciviruses, from the different bat species. Comparisons to published sequences indicate that the bat alphacoronaviruses belong to three different subgenera—i.e., Pedacovirus, Nyctacovirus, and Myotacovirus—that the astroviruses may be new species in the genus Mamastrovirus, and that the polyomavirus could also be a new species, but unassigned to a genus. Furthermore, several viruses of invertebrates—including two Rhopalosiphum padi (aphid) viruses and a Kadipiro virus—present in the faecal material were assembled. Interestingly, this is the first detection in Europe of a Kadipiro virus.

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Section: Introductionmentioning

confidence: 99%

Full-Genome Sequences of Alphacoronaviruses and Astroviruses from Myotis and Pipistrelle Bats in Denmark

Lazov

Belsham

Bøtner

et al. 2021

Viruses

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“…6,7 Cases of the disease have since been reported in the Middle East, North Africa, Europe, East Asia, and the United States of America. 8,9 Since September 2012, 2040 consecutive cases of MERS have been identified by the World Health Organization, with 712 deaths. 10,11 Virology and Pathogenesis MERS-CoV is a member of the Coronaviridae family of viruses.…”

Section: Observation Historymentioning

confidence: 99%

“…In humans, it is expressed in the lower respiratory tract, while in camels it is found in the upper respiratory tract. 9 This virus has the ability to infect multiple cell lineages, and although the epithelial respiratory cells are most susceptible to viral multiplication, 7 it is also seen in human macrophages, dendritic cells, and hepatocytes, as well as in the intestine and renal tubules. DPP4 is found mostly in type 1 and type 2 cells, alveolar macrophages, vascular endothelium, and plural mesothelia.…”

Section: Observation Historymentioning

confidence: 99%

“…The rest of the cases were reported in the United Kingdom, Germany, Egypt, Italy, Malaysia, Greece, South Korea, the Netherlands, France, and the United States of America. 8,9 Most cases were either reported in the Middle East or had direct connection to a primary case of infection in the Middle East. Secondary local transmission following importation was documented in the United Kingdom, France, and Tunisia 2 (Figure 1).…”

Section: Epidemiologymentioning

confidence: 99%

See 1 more Smart Citation

<p>Middle East Respiratory Syndrome – What Every Otolaryngologist Should Know: A Review</p>

Alnemare¹

2020

IJGM

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In this study, we illustrate the history of Middle East respiratory syndrome corona virus (MERS-CoV) infection from the first reported case to the disease's outbreak and subsequent worldwide decline, with the aim of briefly defining the problem for the benefit of otolaryngologists. MERS-CoV belongs to the Coronaviridae family and causes a zoonotic disease, MERS, with strong camel to human and weak human to human transmission. The first documented case of MERS was reported in Saudi Arabia in June 2012. Viral replication produces inflammatory markers targeting T lymphocytes, with apoptosis being the end result. Nevertheless, the pathogenesis of this virus is not yet fully understood. The main symptomatic appearance is of mild lower respiratory tract infection with dyspnea and persistent cough in addition to systemic manifestations. The diagnosis is mainly based on the use of polymerase chain reaction for the detection of viral ribonucleic acid in the sputum or tracheal fluids. Otolaryngologic treatment mainly involves supportive adjuvant usage of interferon or antiviral drugs; however, approximately one-third of patients may not survive, and, therefore, otolaryngologists should be familiar with and remain mindful of the disease.

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“…According to the data available in the literature, coronavirus infection has been found in 11 out of 18 groups of bat families (particularly insectivorous families). The presence of alpha coronaviruses has been reported in some European countries, on the American continent, Australia, Asia and Africa, while the presence of beta coronaviruses has been found in Latin America (Mexico), Africa (Kenya, Madagascar and the southern region of the continent), Asia (Thailand, China, Philippines), the Middle East and the European continent (Italy, Finland) [30]. Bats caused the spread of both the SARS virus in China and MERS-CoV in the Middle East, thus starting global epidemics in 2002 and 2012 [5,31].…”

Section: Batsmentioning

confidence: 99%

Characteristics and Occurrence of Coronaviruses in Humans and Animals

Weiner¹,

Tarasiuk²

2020

hpc

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Authors' contribution Wkład autorów: A. Study design/planning zaplanowanie badań B. Data collection/entry zebranie danych C. Data analysis/statistics dane-analiza i statystyki D. Data interpretation interpretacja danych E. Preparation of manuscript przygotowanie artykułu F. Literature analysis/search wyszukiwanie i analiza literatury G. Funds collection zebranie funduszy Summary Coronaviruses occurring in humans and animals are a diverse group of pathogens, characterized by high variability and tropism. The most serious animal diseases caused by coronaviruses include equine coronavirus disease (E-CoV), canine coronavirus disease (C-CoV), rabbit enteric coronavirus disease (Rb-CoV), infectious bronchitis in poultry (IB-CoV), epizootic catarrhal enteritis in ferrets, in pigs: transmissible gastroenteritis coronavirus disease (TGE), human enteric coronavirus disease (HE-CoV), and porcine epidemic diarrhea (PED), in cattle (Bo-CoV): neonatal calf diarrhea, respiratory tract infections, winter dysentery in cattle, in cats: feline enteric coronavirus disease (FE-CoV) and feline infectious peritonitis (FIP-CoV). To date, three major epidemics causing severe respiratory diseases in humans (SARS-CoV-1, MERS-CoV, SARS-CoV-2) have been reported. Due to the high morbidity and mortality rate, coronavirusinduced diseases in animals result in serious economic losses. The current human COVID-19 pandemic demonstrates the need for action to modernize and improve diagnostics in this area, but also to develop innovative immunoprophylactic and therapeutic methods.

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First Report of Coronaviruses in Northern European Bats

Cited by 24 publications

References 12 publications

Full-Genome Sequences of Alphacoronaviruses and Astroviruses from Myotis and Pipistrelle Bats in Denmark

Full-Genome Sequences of Alphacoronaviruses and Astroviruses from Myotis and Pipistrelle Bats in Denmark

<p>Middle East Respiratory Syndrome – What Every Otolaryngologist Should Know: A Review</p>

Characteristics and Occurrence of Coronaviruses in Humans and Animals

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