First Report of Coexistence of Two Ectopic Pituitary Tumors: Rathke Cleft Cyst and Silent Adrenocorticotropic Hormone Adenoma

Pojskić, Mirza; Zbytek, Blazej; Beckford, Neal S.; Boop, Frederick A.; Arnautović, Kenan I.

doi:10.1016/j.wneu.2017.05.070

Cited by 9 publications

(5 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, our combined approach provided preservation of all anatomic structures, no evidence of postoperative CSF leak and no evidence of postoperative transient or permanent olfactory loss thus minimizing postoperative discomfort. Overall, our experiences indicate that both microsurgical and endoscopic techniques have merits and should be used as complementary, rather than competing, techniques (32).…”

Section: Microsurgery Vs Endoscopic Surgery and Our Experiences With Combinationmentioning

confidence: 87%

Combined Microsurgical, Endoscopic and Neuronavigation Assisted Transseptal-Transsphenoidal Resection of Pituitary Tumors

Pojskić

Arnautovic

Kovačević

et al. 2021

ama

Self Cite

View full text Add to dashboard Cite

Objective. To describe the technical nuances of multimodal transseptal-transsphenoid surgery for pituitary tumors using a combination of microneurosurgery, neuroendoscopy, and electromagnetic neuronavigation.Materials and Methods. A transnasal approach to the sella is performed endoscopically and widely exposed by an otolaryngologic surgeon. Surgery is next performed by the neurosurgeon with microscope and neuronavigation for microsurgical resection of pituitary tumors. Neuroendoscope is also used at the end of surgery to confirm tumor resection and inspect operative site. During surgery, the patient’s head, angle and height of the microscope, and position of the table are repositionable to allow for multiple angle views. Abdominal fat harvested prior to the procedure is used to ensure cerebrospinal fluid seal.Results. The senior author (KIA) has used the combined approach with 84 consecutive patients. Radical resection was achieved in 66 patients, subtotal in 11, and partial in 7. There were no perioperative complications. Six patients experienced postoperative transient diabetes insipidus. The pituitary gland and stalk were preserved in all cases. Visual symptoms were improved in 78% and endocrinological symptoms in 56% of cases.Conclusion. This combined approach is safe and effective. It increases the efficacy and radicality of surgical resection, helps to preserve the pituitary gland, and improves and resolves preoperatively altered patient hormonal function and impaired vision. It also reduces complications, provides less postoperative pain and discomfort, reduces the surgery time, and enables a shorter hospital-stay.

show abstract

Section: Microsurgery Vs Endoscopic Surgery and Our Experiences With Combinationmentioning

confidence: 87%

Combined Microsurgical, Endoscopic and Neuronavigation Assisted Transseptal-Transsphenoidal Resection of Pituitary Tumors

Pojskić

Arnautovic

Kovačević

et al. 2021

ama

Self Cite

View full text Add to dashboard Cite

show abstract

“…They also revealed that the RCC was adjacent to the pituitary adenoma in seven out of eight of the patients in whom this concurrent association was found and in one of the patients, the cyst enclosed the adenoma 12. Pojskić et al in their 2017 publication claimed to have described the first case of two ectopic pituitary lesions: a RCC and a silent adrenocorticotropic hormone adenoma, found in the sphenoidal sinus 13…”

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

“…12 Pojskić et al in their 2017 publication claimed to have described the first case of two ectopic pituitary lesions: a RCC and a silent adrenocorticotropic hormone adenoma, found in the sphenoidal sinus. 13 Azarpira et al reported a concurrent finding of RCC and a combined pituitary adenoma with gangliocytoma in a 50-year-old woman in their 2013 publication. 14 Tamura et al in their publication in 2014 described a concurrent suprasellar RCC and a GH-producing pituitary adenoma in a 53-year-old man who was earlier assessed on his hospital visit with a lacunar infarction in the left basal ganglia.…”

Section: Case Reportmentioning

confidence: 98%

See 1 more Smart Citation

Concurrent growth hormone-producing pituitary adenoma and Rathke’s cleft cyst

2022

View full text Add to dashboard Cite

show abstract

“…Generally speaking, recurrence rates after surgical approach of RCC can assume values up to one-third of cases -being correlated with factors such as the shape of enhancement of the cyst wall, existence of squamous metaplasia, signs of chronic inflammation or stratified epithelium, fierceness of cyst wall resection, and the use of fat graft in an eventual repair [6,7]. When compared to RCC, the intrasphenoidal subtype does not seem to present different clinical features that can easier the pre-operative diagnostic process [9][10][11][12][13]. As RCC presents in the posterior wall of the sphenoid sinus, usually this cannot be properly evaluated in the fibroscopy, except if there was a previous intervention in this area with opening of the anterior portion of the sphenoid sinus [18].…”

Section: Table 1: Summary Of the Intrasphenoidal Rathke's Cleft Cyst ...mentioning

confidence: 99%

Intrasphenoidal Rathke’s Cleft Cyst: An Uncommon Feat

Machado¹,

Silva²,

Silva³

et al. 2023

Cureus

View full text Add to dashboard Cite

Usually occurring entirely intrasellarly or extending suprasellarly (intra-suprasellar), Rathke's cleft cysts (RCCs) can present with an intrasphenoidal location. Extrasellar positions are rare. To date, only seven patients with intrasphenoidal RCC have been reported in the literature. Despite the rarity of the condition and the lack of pathognomonic radiological features, preoperative diagnosis remains challenging. A transsphenoidal approach can be adopted to treat this type of cyst, which has great clinical relevance. Awareness of this different presentation of RCC before respective management may be of value in its approach. Intrasphenoidal RCC should be diagnosed preoperatively and the surgical approach should be changed accordingly by aspiration and partial removal before the histological examination.

show abstract

First Report of Coexistence of Two Ectopic Pituitary Tumors: Rathke Cleft Cyst and Silent Adrenocorticotropic Hormone Adenoma

Cited by 9 publications

References 39 publications

Combined Microsurgical, Endoscopic and Neuronavigation Assisted Transseptal-Transsphenoidal Resection of Pituitary Tumors

Combined Microsurgical, Endoscopic and Neuronavigation Assisted Transseptal-Transsphenoidal Resection of Pituitary Tumors

Concurrent growth hormone-producing pituitary adenoma and Rathke’s cleft cyst

Intrasphenoidal Rathke’s Cleft Cyst: An Uncommon Feat

Contact Info

Product

Resources

About