First report of an antifungal amidase from <i>Peltophorum ptercoarpum</i>

Lam, Sze‐Kwan; Ng, Tzi Bun

doi:10.1002/bmc.1312

Cited by 13 publications

(6 citation statements)

References 48 publications

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“…These experimental results get nice correlation with a previous investigation 30 where antimicrobial activity of methanol extract of P. pterocarpum flowers was found against B. subtilis, S. aureus, S. epidermidis, E. faecalis, E. coli, P. aeruginosa, K. pneumoniae, P. vulgaris, and C. albicans at the concentration of 5 mg/mL. Lam & Ng 26 isolated an amidase, peltopterin, from P. pterocarpum seeds and found its antifungal activity against Rhizotonia solani in the pH range 0-14 and temperature range of 25-100°C 26 . This amidase impeded mycelial growth of this fungus with an IC 50 of 0.65 μM.…”

Section: Chemical Constituents: Chemical Constituents (Structures Shosupporting

confidence: 89%

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2014

IJPSR

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The present work offers a review addressing the detailed chemistry and pharmacology of Peltophorum pterocarpum (belonging to Fabaceae family) regarded as one of the most significant plant species in traditional system of medicine. The plant is used in different parts of the world for the treatment of several ailments like stomatitis, insomnia, skin troubles, constipation, ringworm, insomnia, dysentery, muscular pains, sores, and skin disorders and is the source of a diverse kind of chemical constituents such as aliphatic alcohols, fatty acids, amino acids, terpenoids, phenolics, flavonoids, alkaloids, steroids etc. The isolated phytochemicals as well as different extracts exhibited numerous biological activities including antimicrobial, antioxidant, cytotoxic, aldose reductase inhibition and antiglycaemic activities. Hence, up todate information on the chemical and pharmacological knowledge on this plant may be helpful to guide researchers anticipating to undertake further investigations in these directions. The present review covers literature up to middle of 2013 and enlists 42 references.

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Section: Chemical Constituents: Chemical Constituents (Structures Shosupporting

confidence: 89%

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2014

IJPSR

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“…The antifungal potency toward F. oxysporum was reflected in an IC 50 value of 8.3 μ m . The antifungal potency of CsPR10 is similar to that displayed by other antifungal proteins (Lam & Ng 2009, 2010; Fang et al. 2010; Ye & Ng 2009).…”

Section: Resultssupporting

confidence: 56%

Molecular cloning and characterisation of a pathogenesis‐related protein CsPR10 from Crocus sativus

2011

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Plants have developed many mechanisms to protect themselves against most potential microbial pathogens and diseases. Among these mechanisms, pathogenesis-related proteins are produced as part of the active defence to prevent attack. In this study, a full-length cDNA encoding the CsPR10 protein was identified in fresh saffron stigmas (Crocus sativus). The deduced amino acid sequence from the nucleotide sequence of the coding region showed homology with PR10 proteins. The clone expressed as a protein in fusion with a GST tag produced a 47-kDa protein in E. coli. CsPR10 had ribonuclease activity, with features common to class II-type ribonucleases; its specific activity was quantified as 68.8 U·mg(-1) protein, thus falling within the range of most PR10 proteins exhibiting RNase activity. Antifungal activity of CsPR10 was assayed against Verticillium dahliae, Penicillium sp. and Fusarium oxysporum. CsPR10 inhibited only F. oxysporum growth, and antifungal potency was reflected in a IC(50) of 8.3 μm. Expression analysis showed the presence of high transcript levels in anther and tepal tissues, low levels in stigmas and roots, and no signal detected in leaves. This protein seems to be involved in the active defence response through activation of the jasmonic acid pathway.

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“…Its antifungal activity was thermostable and pH stable. It causes chitin deposition at hyphal tips in R. solani (Lam and Ng 2010b). Ib-AMPs from Impatiens balsamina seeds are 20-mer antifungal and antibacterial peptides with a well-defined loop structure stabilized by two disulfide bonds (Patel et al 1998).…”

Section: Other Antifungal Proteinsmentioning

confidence: 99%

Plant antifungal proteins and their applications in agriculture

Yan

Yuan

Jiang

et al. 2015

Appl Microbiol Biotechnol

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Fungi are far more complex organisms than viruses or bacteria and can develop numerous diseases in plants that cause loss of a substantial portion of the crop every year. Plants have developed various mechanisms to defend themselves against these fungi which include the production of low-molecular-weight secondary metabolites and proteins and peptides with antifungal activity. In this review, families of plant antifungal proteins (AFPs) including defensins, lectins, and several others will be summarized. Moreover, the application of AFPs in agriculture will also be analyzed.

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First report of an antifungal amidase from Peltophorum ptercoarpum

Cited by 13 publications

References 48 publications

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Molecular cloning and characterisation of a pathogenesis‐related protein CsPR10 from Crocus sativus

Plant antifungal proteins and their applications in agriculture

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