First-principle studies of the geometries and electronic properties of Cu_mSi_n(2 ⩽m+n⩽ 7) clusters

Copper‐ or Iron‐Catalyzed Arylation of Phenols from respectively Aryl Chlorides and Aryl Iodides

“…ly here, is the iron-catalyzed arylation of phenols from aryl iodides. [7] A systematic study was first undertaken by choosing 3,5dimethylphenol as a model substrate (synthesis of 2 f, Table 1). Our first test allowed us to check the result presented in Scheme 1, because we observed that under quite similar conditions the arylation of dimethylphenol from chlorobenzene was indeed possible even in the presence of a lower quantity (10 %) of iron catalyst ( Table 1, entry 1).…”

“…Although the aryl iodides are much less challenging than the chlorides, this catalytic system is very interesting because it constitutes the first report of C À O coupling catalyzed by iron. [7,10] A final example shows the advantage of complementary use of copper and iron in this catalyst system: using both [a] Yield of isolated product. Scheme 2.…”

“…Ligand 1/Fe-catalyzed arylation of phenols from aryl iodides (isolated yields in brackets). [7] www.chemeurj.org metals with ligand 1 enables a chemoselective one-pot synthesis of an unsymmetrical polyether as demonstrated by the preparation of oligomer 3 in 80 % isolated yield (Scheme 3). Such compounds, which are otherwise difficult to synthesize selectively, are important target molecules for the life sciences.…”