First Place: Renal Oxygenation During Robot-Assisted Laparoscopic Partial Nephrectomy: Characterization Using Laparoscopic Digital Light Processing Hyperspectral Imaging

Olweny, Ephrem O.; Faddegon, Stephen; Best, Sara L.; Jackson, Neil; Wehner, Eleanor; Tan, York Kiat; Zuzak, Karel J.; Cadeddu, Jeffrey A.

doi:10.1089/end.2012.0207

Cited by 30 publications

(25 citation statements)

References 20 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tumor-specific arterial branches are microdissected and superselectively clamped with micro-bulldog clips. Selective arterial control is confirmed intraoperatively by color Doppler sonography [69,70], hyperspectral imaging [71,72], or robotic vascular fluorescence imaging [73]. In an initial study of 15 patients, there was no change in estimated GFR (eGFR) [66].…”

Section: Evidence Synthesismentioning

confidence: 99%

A Literature Review of Renal Surgical Anatomy and Surgical Strategies for Partial Nephrectomy

et al. 2015

View full text Add to dashboard Cite

Context A detailed understanding of renal surgical anatomy is necessary to optimize preoperative planning and operative technique and provide a basis for improved outcomes. Objective To evaluate the literature regarding pertinent surgical anatomy of the kidney and related structures, nephrometry scoring systems, and current surgical strategies for partial nephrectomy (PN). Evidence acquisition A literature review was conducted. Evidence synthesis Surgical renal anatomy fundamentally impacts PN surgery. The renal artery divides into anterior and posterior divisions, from which approximately five segmental terminal arteries originate. The renal veins are not terminal. Variations in the vascular and lymphatic channels are common; thus, concurrent lymphadenectomy is not routinely indicated during PN for cT1 renal masses in the setting of clinically negative lymph nodes. Renal-protocol contrast-enhanced computed tomography or magnetic resonance imaging is used for standard imaging. Anatomy-based nephrometry scoring systems allow standardized academic reporting of tumor characteristics and predict PN outcomes (complications, remnant function, possibly histology). Anatomy-based novel surgical approaches may reduce ischemic time during PN; these include early unclamping, segmental clamping, tumor-specific clamping (zero ischemia), and unclamped PN. Cancer cure after PN relies on complete resection, which can be achieved by thin margins. Post-PN renal function is impacted by kidney quality, remnant quantity, and ischemia type and duration. Conclusions Surgical renal anatomy underpins imaging, nephrometry scoring systems, and vascular control techniques that reduce global renal ischemia and may impact post-PN function. A contemporary ideal PN excises the tumor with a thin negative margin, delicately secures the tumor bed to maximize vascularized remnant parenchyma, and minimizes global ischemia to the renal remnant with minimal complications. Patient summary In this report we review renal surgical anatomy. Renal mass imaging allows detailed delineation of the anatomy and vasculature and permits nephrometry scoring, and thus precise, patient-specific surgical planning. Novel off-clamp techniques have been developed that may lead to improved outcomes.

show abstract

Section: Evidence Synthesismentioning

confidence: 99%

A Literature Review of Renal Surgical Anatomy and Surgical Strategies for Partial Nephrectomy

et al. 2015

View full text Add to dashboard Cite

show abstract

“…[26], laparoscopic digital light processing – Olweny EO. [27], blood stains at the crime scene – Edelman G. [28], prostate cancer detection – Akbari H. [29], histopathological examination of excised tissue - Vasefi F. [30] diabetic foot ulcer - Yudovsky D. [31], cancer detection - Akbari H. [32], and others.…”

Section: Resultsmentioning

confidence: 99%

Automatic method for the dermatological diagnosis of selected hand skin features in hyperspectral imaging

Koprowski

Wilczyński

Wróbel

et al. 2014

BioMedical Engineering OnLine

View full text Add to dashboard Cite

IntroductionHyperspectral imaging has been used in dermatology for many years. The enrichment of hyperspectral imaging with image analysis broadens considerably the possibility of reproducible, quantitative evaluation of, for example, melanin and haemoglobin at any location in the patient's skin. The dedicated image analysis method proposed by the authors enables to automatically perform this type of measurement.Material and methodAs part of the study, an algorithm for the analysis of hyperspectral images of healthy human skin acquired with the use of the Specim camera was proposed. Images were collected from the dorsal side of the hand. The frequency λ of the data obtained ranged from 397 to 1030 nm. A total of 4'000 2D images were obtained for 5 hyperspectral images. The method proposed in the paper uses dedicated image analysis based on human anthropometric data, mathematical morphology, median filtration, normalization and others. The algorithm was implemented in Matlab and C programs and is used in practice.ResultsThe algorithm of image analysis and processing proposed by the authors enables segmentation of any region of the hand (fingers, wrist) in a reproducible manner. In addition, the method allows to quantify the frequency content in different regions of interest which are determined automatically. Owing to this, it is possible to perform analyses for melanin in the frequency range λ E ∈(450,600) nm and for haemoglobin in the range λ H ∈(397,500) nm extending into the ultraviolet for the type of camera used. In these ranges, there are 189 images for melanin and 126 images for haemoglobin. For six areas of the left and right sides of the little finger (digitus minimus manus), the mean values of melanin and haemoglobin content were 17% and 15% respectively compared to the pattern.ConclusionsThe obtained results confirmed the usefulness of the proposed new method of image analysis and processing in dermatology of the hand as it enables reproducible, quantitative assessment of any fragment of this body part. Each image in a sequence was analysed in this way in no more than 100 ms using Intel Core i5 CPU M460 @2.5 GHz 4 GB RAM.

show abstract

“…Furthermore, younger patients had a lower median baseline %HbO 2 and a signifi cantly higher median preoperative eGFR, perhaps refl ective of age-related decline in renal oxygen consumption. No signifi cant associations between %HbO 2 and diabetes, hypertension, and smoking history were observed [ 25 ].…”

Section: Hyperspectral Imagingmentioning

confidence: 92%

“…ing open partial nephrectomy, demonstrating that in the artery+vein group, a lower mean ischemic %HbO 2 was associated with signifi cantly lower eGFR at most recent follow-up on both univariate and multivariate analysis [ 24 ]. Most recently, Olweny et al used a novel laparoscopic DLP ® -HSI system to study renal oxygenation in patients undergoing robotic-assisted laparoscopic partial nephrectomy [ 25 ]. They demonstrated a significant inverse association between baseline %HbO 2 and baseline eGFR as well as between baseline %HbO 2 and eGFR at most recent follow-up ( p < 0.05).…”

Section: Hyperspectral Imagingmentioning

confidence: 99%

Light Reflectance Spectroscopy and Autofluorescence (Kidney and Prostate)

Olweny

Cadeddu

2014

Advances in Image-Guided Urologic Surgery

Self Cite

View full text Add to dashboard Cite

First Place: Renal Oxygenation During Robot-Assisted Laparoscopic Partial Nephrectomy: Characterization Using Laparoscopic Digital Light Processing Hyperspectral Imaging

Abstract: The laparoscopic HSI system successfully characterized dynamic changes in renal oxygenation during RALPN. Intraoperative laparoscopic HSI outcomes have the potential to predict postoperative individual kidney function.

Cited by 30 publications

References 20 publications

A Literature Review of Renal Surgical Anatomy and Surgical Strategies for Partial Nephrectomy

A Literature Review of Renal Surgical Anatomy and Surgical Strategies for Partial Nephrectomy

Automatic method for the dermatological diagnosis of selected hand skin features in hyperspectral imaging

Light Reflectance Spectroscopy and Autofluorescence (Kidney and Prostate)

Contact Info

Product

Resources

About