First pass results of mechanical thrombectomy with two-drop zone NeVa<sup>TM</sup> device

Bajrami, Arsida; Ertugrul, Ozgur; Şenadım, Songül; Erdem, Eren; Baltacıoğlu, Feyyaz; Geyik, Serdar

doi:10.1177/15910199221135309

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Over the last decade, there has been a significant improvement in our understanding of the various clot types [6], the interaction between stent-retrievers and clots [7][8][9], and how both stent-retrievers and clots interact with the vessel wall and in combination during retrieval [10]. This improvement in our understanding has led to the development of stent-retrievers with novel designs [11][12][13][14][15], with the synchronous development of novel aspiration catheters [16][17][18] and various techniques for optimising the MT procedure and first-pass recanalisation.…”

Section: Introductionmentioning

confidence: 99%

The Stream Device—A Retrospective Review of 51 Cases

Kupcs,

Sproge,

Kupca

et al. 2023

JCM

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Mechanical thrombectomy is the gold-standard treatment for patients that have suffered large-vessel occlusion (LVO) stroke. Various different stent-retrievers, aspiration catheters, and techniques have been developed to perform this procedure. We present our initial results regarding the Stream device. Materials and Methods: We performed a retrospective review of a prospectively maintained database at our high-volume centre to identify all patients treated with the Stream device between February 2021 and January 2023. We recorded baseline demographics, NIHSS, ASPECT scores, eTICI scores, complications, and 90-day mRS. Results: We identified 51 patients, 49.0% of whom were male (n = 25), with a median age of 73 (range: 51–89) and a median NIHSS score of 17 (range 4–22), and 68.6% received IV tPA. The median ASPECT score was 10 (range 6–10). Hyperdense clots were seen in 34 cases (66.7%), with a mean clot length of 12 ± 6.2 mm (range 2–26 mm). Clots were located in the anterior circulation in 49 patients. The standard Stream device was used in 78.4% of cases, with Stream 17 being used in 19.6% of cases. The FPE was observed in 25.5% of cases (n = 13), with the mFPE being seen in 31.4% of cases (n = 16). A final eTICI score of ≥2b was achieved in 90.2% of cases (n = 46), and eTICI 2c/3 was seen in 84.3% of cases (n = 43). Furthermore, 24 h CT scans showed that the median ASPECT score was 8 (range 0–10). Good functional outcomes at 90 days (mRS ≤ 2) were achieved in 21.6% of cases (n = 11). Conclusions: The Stream device shows acceptable rates of FPE and mFPE compared to existing devices. Further larger studies are required alongside an understanding of the optimal technique for this device’s use.

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Section: Introductionmentioning

confidence: 99%

The Stream Device—A Retrospective Review of 51 Cases

Kupcs,

Sproge,

Kupca

et al. 2023

JCM

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Evaluation of effectiveness and safety of the multizone NeVaTM stent retriever for mechanical thrombectomy in ischemic stroke

Masthoff,

Krähling,

Akkurt

et al. 2023

Neuroradiology

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Purpose This study aimed to evaluate the effectiveness and safety of the NeVaTM stent retriever as first- and second-line device for mechanical thrombectomy in acute ischemic stroke. Methods In this retrospective single-center study, all consecutive patients that underwent mechanical thrombectomy with NeVaTM stent retriever as first- or second-line device due to intracranial vessel occlusion with acute ischemic stroke between March and November 2022 were included. Results Thirty-nine patients (m=18, f=21) with a mean age of 69.9 ± 13.3 years were treated with the NeVaTM stent retriever. NeVaTM stent retriever was used as first-line device in 24 (61.5%) of patients and in 15 (38.5%) as second-line device. First-pass rate (≥mTICI 2c) of NeVaTM stent retriever was both 66.7% when used as first- or second-line device. Final recanalization rate including rescue strategies was 92.3% for ≥mTICI2c and 94.9% for ≥mTICI2b. No device-related minor or major adverse events were observed. A hemorrhage was detected in 33.3% of patients at 24h post-thrombectomy dual-energy CT, of which none was classified as symptomatic intracerebral hemorrhage. NIHSS and mRS improved significantly at discharge compared to admission (p<0.05). Conclusion The NeVaTM stent retriever has a high effectivity and good safety profile as first- and second-line device for mechanical thrombectomy in acute ischemic stroke.

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Rapidpulse^TM cyclic aspiration system for acute ischemic stroke due to large vessel occlusions

Bajrami,

Geyik,

Ertugrul

et al. 2024

Interv Neuroradiol

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Background The best strategy to achieve optimal reperfusion outcomes during mechanical thrombectomy remains to be defined. The RapidPulseTM Cyclic Aspiration System is a novel technology, delivering high-frequency pulsed vacuum forces to increase the efficiency of aspiration thrombectomy. Methods Prospective, multicenter, open-label, core lab-adjudicated, two-arm study comparing safety and efficacy of a feasibility version of the RapidPulseTM system compared with contemporary controls. Primary endpoint was the rate of mTICI ≥ 2c after first-pass effect (FPE). Additional efficacy endpoints were the rates of mTICI [Formula: see text] 2b after first pass (modified FPE (mFPE)), last pass with study device defined as frontline technical success, and after all passes including rescue therapy. The primary safety endpoints included symptomatic ICH (sICH) within 24 h post-procedure. Results Between February 2022 to December 2022, 80 subjects were consented and enrolled in the study (n = 40 treatment arm, n = 40 control arm). In the intent to treat (ITT) population, mean age was 67.8 ± 11.5 years; 19 (47.5%) were male. Median NIHSS score was 16 (IQR: 13–22). Median ASPECTS score was 9 (IQR: 8–10). The rate of mTICI ≥ 2c after first pass was 53.9% in ITT population (60.0% in per-protocol population) versus 38.5% in the corresponding control population. Functional independence (mRS 0-2) at 90 days was achieved in 61.1% (22/36) in the RapidPulseTM arm and 52.8% (19/36) in the control arm. In the RapidPulseTM arm, no sICH within 24 h and no device-related morbidity or mortality occurred. Conclusion Preliminary data suggests RapidPulseTM Aspiration System is highly effective and safe for recanalization of large vessel occlusions.

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First pass results of mechanical thrombectomy with two-drop zone NeVa^TM device

Cited by 3 publications

References 18 publications

The Stream Device—A Retrospective Review of 51 Cases

The Stream Device—A Retrospective Review of 51 Cases

Evaluation of effectiveness and safety of the multizone NeVaTM stent retriever for mechanical thrombectomy in ischemic stroke

Rapidpulse^TM cyclic aspiration system for acute ischemic stroke due to large vessel occlusions

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First pass results of mechanical thrombectomy with two-drop zone NeVaTM device

Cited by 3 publications

References 18 publications

The Stream Device—A Retrospective Review of 51 Cases

The Stream Device—A Retrospective Review of 51 Cases

Evaluation of effectiveness and safety of the multizone NeVaTM stent retriever for mechanical thrombectomy in ischemic stroke

RapidpulseTM cyclic aspiration system for acute ischemic stroke due to large vessel occlusions

Contact Info

Product

Resources

About

First pass results of mechanical thrombectomy with two-drop zone NeVa^TM device

Rapidpulse^TM cyclic aspiration system for acute ischemic stroke due to large vessel occlusions