“…Attempts have been made to develop better autoradiography systems based on digital position-sensitive detectors. These include the use of phosphor imaging plates (Johnson et al 1990), multiwire proportional chambers (Englert et al 1995), scintillating optical fibres (Gordon et al 1992), microchannel plates (Ljundggren and Strand 1990, 1994, Lees et al 1997, silicon strip detectors (Overdick et al 1997), silicon or gallium arsenide pixel detectors (Heijne et al 1994, Bertolucci et al 1997 and charge coupled device (CCD) scintillator combinations (Charon et al 1988, Karellas et al 1992, 1993. All of these systems, except the phosphor imaging plates, provide rapid, on-line, real-time imaging with good linearity and sensitivity, but only the CCD based systems have a spatial resolution approaching that of film.…”