First molecular detection and characterization of Akabane virus in small ruminants in Turkey

Oğuzoğlu, Tuba Çiğdem; Toplu, N.; Koç, Bahattin Taylan; Doğan, Fırat; Epikmen, Erkmen Tuğrul; İpek, Emrah; Akkoç, Ayşe Nur

doi:10.1007/s00705-015-2536-6

Cited by 9 publications

(7 citation statements)

References 25 publications

(35 reference statements)

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“…AKAV was first described in the 1950s in Japan and is now endemic in large parts of Asia, the Middle East, Australia and Africa [34,57,85,86]. The virus may induce abnormal courses of pregnancy and fetal malformation in ruminants as described for both AKAV and SBV [34].…”

Section: The Genus Orthobunyavirusmentioning

confidence: 99%

Culicoides Biting Midges—Underestimated Vectors for Arboviruses of Public Health and Veterinary Importance

Sick

Beer

Kampen

et al. 2019

Viruses

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Culicoides biting midges, small hematophagous dipterans, are the demonstrated or putative vectors of multiple arboviruses of veterinary and public health importance. Despite its relevance in disease spread, the ceratopogonid genus Culicoides is still a largely neglected group of species, predominantly because the major human-affecting arboviruses are considered to be transmitted by mosquitoes. However, when a pathogen is detected in a certain vector species, a thorough search for further vectors often remains undone and, therefore, the relevant vector species may remain unknown. Furthermore, for many hematophagous arthropods, true vector competence is often merely suspected and not experimentally proven. Therefore, we aim to illuminate the general impact of Culicoides biting midges and to summarize the knowledge about biting midge-borne disease agents using the order Bunyavirales, the largest and most diverse group of RNA viruses, as an example. When considering only viruses evidentially transmitted by Culicoides midges, the Simbu serogroup (genus Orthobunyavirus) is presumably the most important group within the virus order. Its members are of great veterinary importance, as a variety of simbuviruses, e.g., the species Akabane orthobunyavirus or Schmallenberg orthobunyavirus, induces severe congenital infections in pregnant animals. The major zoonotic representative of this serogroup occurs in South and Central America and causes the so-called Oropouche fever, an acute febrile illness in humans.

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Section: The Genus Orthobunyavirusmentioning

confidence: 99%

Culicoides Biting Midges—Underestimated Vectors for Arboviruses of Public Health and Veterinary Importance

Sick

Beer

Kampen

et al. 2019

Viruses

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“…). Molecular detection of AKAV RNA has also been detected from biting midges and affected animals in Israel (Stram et al, 2004) and Turkey (Oğuzoğlu et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

A large-scale serological survey of Akabane virus infection in cattle, yak, sheep and goats in China

Wang

Blasdell

Yin

et al. 2017

Veterinary Microbiology

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Please cite this article as: Wang, J., Blasdell, K.R., Yin, H., Walker, P.J.,A large-scale serological survey of Akabane virus infection in cattle, yak, sheep and goats in China, Veterinary Microbiology (2017), http://dx.doi.org/10. 1016/j.vetmic.2017.05.014 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Japan and Korea, may also be present in cattle in China.

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“…La infección por AKAV se observa generalmente en Australia, los países de Oriente Medio, el sudeste de Asia y algunos países africanos (10). También, la presencia de AKAV en pequeños rumiantes en Turquía se ha informado en estudios previos (16,17,18). Además de los factores relacionados con el ecosistema, como el calentamiento global, los cambios estacionales y la presencia de áreas húmedas, el transporte de animales, los cambios en la estructura demográfica y el aumento de los viajes humanos desempeñan un papel importante en la aparición de enfermedades transmitidas por vectores, tales como AKAV (19,20,21).…”

Section: Discussionunclassified

“…Por lo tanto, AKAV no se detectó en 2018 y 2019. AKAV se detectó en la región occidental de Turquía en marzo en un estudio realizado por Oguzoglu et al (17). En el presente estudio, se detectó AKAV en enero, febrero, abril, mayo y julio.…”

Section: Discussionunclassified

Molecular investigation of most important viruses causing abortion in small ruminants: the importance of akabane virus

Çağırgan¹,

Pekmez²,

Kaplan³

et al. 2021

Rev MVZ Córdoba

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Objective. This study was aimed to investigate the presence of pestivirus, schmallenberg virus (SBV), akabane virus (AKAV), and determined the seasonal distribution in small ruminant abortion cases Materials and Methods. A total of 164 small ruminant aborted fetuses (39 goats and 125 sheep) were investigated in West Turkey between the years of 2015 and 2019. While the SBV and pestivirus were examined with real-time RT-PCR, the AKAV was examined with nested-PCR. Results. In this study, while four sheep (2.3%) were found to be pestivirus positive, nine sheep and one goat (5.9%) were found to be AKAV positive. SBV was detected in none of the animals. According to the results of the studies carried out, AKAV, a vector-borne virus, was detected more than other viruses in sheep and goat abortions in West Turkey. A positive akabane virus sample detected in sheep fetuses was sequenced based on the partial S segment. This sample showed 99-100% similarity to the Adana-15, Aksu-1, and Aksu-2 isolates previously detected in Southern Turkey. Phylogenetic analysis showed that the sequenced isolate in this study was clustered within genogroup Ib. Another important piece of data revealed in this study was the determination of the seasonal distribution of sheep and goat abortions. Abortion cases which started to increase in November reached a peak in February and declined till August. Conclusions. This is the first study in the Aegean Region (including seven provinces) in which three important viral agents were simultaneously investigated in small ruminant aborted fetuses.

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First molecular detection and characterization of Akabane virus in small ruminants in Turkey

Cited by 9 publications

References 25 publications

Culicoides Biting Midges—Underestimated Vectors for Arboviruses of Public Health and Veterinary Importance

Culicoides Biting Midges—Underestimated Vectors for Arboviruses of Public Health and Veterinary Importance

A large-scale serological survey of Akabane virus infection in cattle, yak, sheep and goats in China

Molecular investigation of most important viruses causing abortion in small ruminants: the importance of akabane virus

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