First Molecular Confirmed Outbreak of Malignant Ovine Theileriosis in Sheep from North India

Moudgil, Pallavi; Grakh, Kushal; Kumar, Raj; Sharma, Maneesh; Gupta, Renu; Jindal, Naresh

doi:10.1007/s11686-023-00684-z

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…Similarly, no signi cant difference was observed between various hematological parameters among male and female Theileria-positive sheep.Comparisons of average hematological parameters inTheileria-positive sheep from the four blocks of Kendrapara district revealed a signi cant difference (P < 0.05) in PCV and Eosinophil count, while no statistically substantial difference (P > 0.05) was found in other parameters, including Hb, TLC, TEC, Neutrophils, Lymphocytes, Basophils, Monocytes, MCV, and MCHC. A reduction in the levels of Hb and TEC was noted, accompanied by PCV values falling below the expected range, aligning with the ndings documented by Ayaz et al, (2023), Riaz and Tasawar (2017), and Jayalakshmi et al, (2022).This highlights PCR's 6% higher sensitivity compared to traditional blood smear examination, making it effective even in subclinical infections.Several researchers made similar observations like Mamatha et al, (2017), Dhaygude et al, (2020),Moudgil et al, (2023),Nangru et al, (2022Nangru et al, ( , 2023. The identi ed Theileria species bears a striking resemblance to T. luwenshuni, which is consistent with the recognized patterns of host pathology observed in sheep and goats.…”

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confidence: 69%

“…Temperature increases contribute to shifts in tick distribution, yet alterations in rainfall patterns might exert a more signi cant in uence compared to temperature uctuations (Estrada-Peña et al 2012). Malignant theileriosis can also be passed down from parent to offspring through vertical transmission (Moudgil et al 2023). The prevalence of the disease peaks during summer months due to favorable ecological conditions and climatic stress, which promote the breeding and proliferation of ticks (Mohsin et al 2022; Irfan et al 2023).…”

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confidence: 99%

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Cross-sectional study on prevalence of theileriosis in Kendrapada sheep, Odisha

Mohanty,

Acharya,

Mishra

et al. 2024

Preprint

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Ovine theileriosis represents a significant threat to both animal welfare and global agricultural productivity, particularly impacting economically disadvantaged farmers. Vector-borne haemoparasitic diseases like theileriosis have a profound effect on the health of livestock, leading to increased illness and mortality, especially in the coastal regions of Odisha. This research aimed to investigate and comprehend the prevalence, clinical manifestations, hematological and biochemical parameters, as well as molecular aspects of theileriosis in sheep from Kendrapada. Among 148 blood samples collected from Kendrapada sheep across four blocks, 13% tested positive for theileriosis, indicating a notable prevalence. The prevalence rate was highest among sheep aged 1–4 years (19%), followed by those younger than 1 year (17.9%) and older than 4 years (13.3%). Female sheep exhibited a higher prevalence (19%) compared to males (16%). Block-wise prevalence was highest in Aul (27.9%), followed by Marshaghai (19.4%), Kendrapada (16.1%), and Derabish (5.88%). Hematological analysis revealed deviations in parameters such as hemoglobin, total erythrocyte count, total leukocyte count, and mean corpuscular volume, while packed cell volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and differential leukocyte count remained within normal ranges. Significant differences (P < 0.05) were observed in various parameters between Theileria-positive and negative sheep. However, there were no substantial variations noted among different age groups and genders of Theileria-positive sheep. PCR analysis identified an overall incidence of theileriosis at 17.57% in the study population, with sequences closely resembling Theileria luwenshuni isolates. This study confirms the high variability of the 18S small subunit rRNA gene among Theileria spp.

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confidence: 69%

Section: Introductionmentioning

confidence: 99%

Cross-sectional study on prevalence of theileriosis in Kendrapada sheep, Odisha

Mohanty,

Acharya,

Mishra

et al. 2024

Preprint

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Molecular Detection of Theileria ovis, Anaplasma ovis, and Rickettsia spp. in Rhipicephalus turanicus and Hyalomma anatolicum Collected from Sheep in Southern Xinjiang, China

Li,

Xieripu

et al. 2024

Pathogens

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The Xinjiang Uygur Autonomous Region (Xinjiang) borders eight countries and has a complex geographic environment. There are almost 45.696 million herded sheep in Xinjiang, which occupies 13.80% of China’s sheep farming industry. However, there is a scarcity of reports investigating the role of sheep or ticks in Xinjiang in transmitting tick-borne diseases (TBDs). A total of 894 ticks (298 tick pools) were collected from sheep in southern Xinjiang. Out of the 298 tick pools investigated in this study, Rhipicephalus turanicus (Rh. turanicus) and Hyalomma anatolicum (H. anatolicum) were identified through morphological and molecular sequencing. In the southern part of Xinjiang, 142 (47.65%), 86 (28.86%), and 60 (20.13%) tick pools were positive for Rickettsia spp., Theileria spp., and Anaplasma spp., respectively. Interestingly, the infection rate of Rickettsia spp. (73%, 35.10%, and 28.56–41.64%) was higher in Rh. turanicus pools than in H. anatolicum pools (4%, 4.44%, and 0.10–8.79%) in this study. Fifty-one tick pools were found to harbor two pathogens, while nineteen tick pools were detected to have the three pathogens. Our findings indicate the presence of Rickettsia spp., Theileria spp., and Anaplasma spp. potentially transmitted by H. anatolicum and Rh. turanicus in sheep in southern Xinjiang, China.

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First Molecular Confirmed Outbreak of Malignant Ovine Theileriosis in Sheep from North India

Cited by 2 publications

References 29 publications

Cross-sectional study on prevalence of theileriosis in Kendrapada sheep, Odisha

Cross-sectional study on prevalence of theileriosis in Kendrapada sheep, Odisha

Molecular Detection of Theileria ovis, Anaplasma ovis, and Rickettsia spp. in Rhipicephalus turanicus and Hyalomma anatolicum Collected from Sheep in Southern Xinjiang, China

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