First Metatarsophalangeal Joint Arthrodesis: Comparison of Mesenchymal Stem Cell Allograft versus Autogenous Bone Graft Fusion Rates

Anderson, John J.; Jeppesen, Nathan; Hansen, Myron; Brady, Chad; Gough, Adam; Fowler, Zflan

doi:10.4236/ss.2013.45051

Cited by 9 publications

(6 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the tools proposed purpose was for evaluation of nonunion risk in any foot and ankle surgery, the validation study only examined ankle arthrodesis, so its direct applicability to first MTP fusion is limited. Supporting that study's conclusion, however, are the findings by Anderson et al, 30 who in 2013 retrospectively examined 165 patients undergoing first MTP fusion. This study found an overall nonunion rate of 6.7% (11/165) and reported significantly higher rates of nonunion in obese patients (2/5, 40%) compared to non-obese patients.…”

Section: Discussionmentioning

confidence: 71%

“…24 Despite the data suggesting that obesity as a risk factor for outcomes in the foot and ankle literature, there is a paucity of data regarding outcomes of 1st MTP joint arthrodesis among obese patients. [30][31][32] Given the magnitude of this epidemic and the rise of the aging population, it is important to understand how obesity affects outcomes following 1st MTPJ arthrodesis. The purpose of this study is to evaluate both clinical and patient-reported outcomes following 1st MTP joint arthrodesis in obese patients and compare these results with non-obese patients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Obesity on Patient-Perceived Outcomes After First Metatarsophalangeal Joint Arthrodesis

Webb

Manz

Fuqua

et al. 2022

Foot & Ankle Specialist

View full text Add to dashboard Cite

Background: While first metatarsophalangeal joint (MTPJ) arthrodesis is a common and effective procedure, there is a paucity of studies examining obesity’s effect on outcomes of 1st MTPJ arthrodesis. This study’s purpose was to evaluate patient-reported outcomes following 1st MTPJ arthrodesis in obese versus non-obese patients. Methods: A retrospective cohort study of 94 patients undergoing first MTPJ fusion over the age of 18 with a diagnosis of hallux valgus or hallux rigidus was performed. Surgical and postoperative outcomes were examined preoperatively and at 6 and 12 months follow-up via Visual Analog Pain scale (VAS), and Short Form 36 (SF-36) surveys, and data were stratified into 2 patient groups: BMI < 30 (n = 62, mean age 63.9 ± 9.1 and ≥ 30 (n = 32, mean age 61.9 ± 8.4). Results: Average overall VAS and SF-36 physical component scores improved significantly at 6 months ( P < .001, .006) and 1 year postoperative visits ( P < .001, .007) with no differences in survey scores, outcomes, or complications between weight groups. Conclusion: Our study showed first MTPJ fusion improves short-term pain and physical quality-of-life in arthritic obese and non-obese patients without differences in nonunion, complications, or patient-reported measures. Level of Evidence: Level III, Prognostic, Case-Control Study

show abstract

Section: Discussionmentioning

confidence: 71%

Section: Introductionmentioning

confidence: 99%

Effect of Obesity on Patient-Perceived Outcomes After First Metatarsophalangeal Joint Arthrodesis

Webb

Manz

Fuqua

et al. 2022

Foot & Ankle Specialist

View full text Add to dashboard Cite

show abstract

“…Bone graft material was used in 12 patients. There was also no significance between the grafting versus non-grafting patients ( 57 ). The average time for radiographic union was 7.7 weeks (range 4–14), and average postoperative months of follow-up was 45 months (range 24–121).…”

Section: Resultsmentioning

confidence: 93%

Complication rates in diabetics with first metatarsophalangeal joint arthrodesis

Anderson

Hansen²,

Rowe³

et al. 2014

Diabetic Foot & Ankle

Self Cite

View full text Add to dashboard Cite

BackgroundFirst metatarsophalangeal joint (MTPJ) arthrodesis has been an effective surgical entity when indicated, but a range of severe to mild complications can occur from this procedure. Patients with diabetes mellitus have an increased risk in surgical complications, most commonly associated with soft tissue and bone healing, when compared to non-diabetic patients. The purpose of this study was to evaluate the complication rates of first MTPJ arthrodesis in diabetic patients and compare them to the existing complication rates for the procedure.MethodsA retrospective chart review was done on 76 diabetic patients, from June 2002 to August 2012. Thirty-two males and 44 females were included in the study. The authors evaluated many variables that could impact postoperative complications, including age, gender, bone graft incorporation, hemoglobin A1c, tobacco use, body mass index, peripheral neuropathy, hallux extensus, hallux interphalangeal arthritis, and rheumatoid arthritis, and compared them with the complication findings. Patient follow-up was no less than 24 months.ResultsOverall, approximately two-thirds of the patients had no complications and 35.5% of patients had at least one mild or moderate complication. Of the non-union and mal-union complications, 80 and 70% had peripheral neuropathy, respectively. One hundred percent of the patients that had mal-positions or hardware failure also had peripheral neuropathy. No severe complications were seen during follow-up. Only two of the moderate complications needed revisions, and the rest of those with moderate complications were asymptomatic.ConclusionIn conclusion, first MTPJ arthrodesis is overall an effective and beneficial procedure in patients with diabetes mellitus. Diabetic patients with peripheral neuropathy have an increased risk for mild and moderate complications.

show abstract

“…As recombinant DNA science and technology have advanced, there has been a plethora of orthobiologics on the market [10]- [14]. Surgeons have been searching for an optimal allograft to hold up to the measured gold standard of bone graft, which is human autograft [2] [15] [16]. A multitude of bone graft substitutes have been applied and used to avoid problems with donor site complications [17].…”

Section: Introductionmentioning

confidence: 99%

Initial Experience with Tricortical Iliac Crest Bone Graft and Human Amniotic Allograft in Evans Calcaneal Osteotomy

Anderson¹,

Gough²,

Hansen³

et al. 2015

SCD

View full text Add to dashboard Cite

Background: Adult acquired flatfoot deformity is generally mediated with an Evans procedure where a wedge of bone is placed into the calcaneus to better align the foot and decrease the deformity. The purpose of this study was to assess the efficacy and safety of human amniotic allograft applied to allogeneic tri-cortical grafts in Evans calcaneal osteotomy. Methods: The medical records of patients who had Evans calcaneal osteotomy with implantation of tri-cortical iliac crest bone graft with human anmiotic allograft for surgical management of adult acquired flatfoot deformity with 2 years follow-up data were reviewed. Results: A total of 63 patients (mean age: 33.3 yr, range: 18-66 yr) were enrolled with adult acquired flatfoot deformity. Median time to weightbearing was 6 weeks. Time to wearing normal shoes was 10 weeks, and time to radiographic healing was 16 weeks. Conclusions: The use of human amniotic allograft did not diminish the long term outcome of procedure or the short term benchmarks for healing after surgery. There were no nonunion, wound dehiscence, infection, or allergic or immune reaction reported. This retrospective study demonstrated that tri-cortical iliac crest bone graft and HAA could be safely used in Evans calcaneal osteotomy with favorable results.

show abstract

First Metatarsophalangeal Joint Arthrodesis: Comparison of Mesenchymal Stem Cell Allograft versus Autogenous Bone Graft Fusion Rates

Cited by 9 publications

References 9 publications

Effect of Obesity on Patient-Perceived Outcomes After First Metatarsophalangeal Joint Arthrodesis

Effect of Obesity on Patient-Perceived Outcomes After First Metatarsophalangeal Joint Arthrodesis

Complication rates in diabetics with first metatarsophalangeal joint arthrodesis

Initial Experience with Tricortical Iliac Crest Bone Graft and Human Amniotic Allograft in Evans Calcaneal Osteotomy

Contact Info

Product

Resources

About