First Isolation of Burkholderia cepacia from a Deep Neck Abscess in a Diabetic Patient Successfully Treated with Hyperbaric Oxygen

Cervical necrotizing fasciitis: A novel clinical presentation of Burkholderia cepacia infection

“…Burkholderia cepacia was isolated in cases of chronic suppurative otitis media complicated by cerebellar and cerebello-pontine abscesses, 4 pharyngeal infection, 5 and paediatric neck infection. 6 In 2005, Fadini et al 7 reported the first isolation of Burkholderia cepacia from a deep neck abscess in a diabetic patient. Although the authors emphasized the role played by hyperbaric oxygen therapy, deep neck infection with initial mediastinic involvement was solved by surgical drainage and broad-spectrum intravenous antibiotic therapy, as abundantly reported by literature.…”

Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence

“…Cephalosporins other than ceftazidime were administered in six cases (10.5%); two patients received ceftriaxone [58,65], two received cefepime [41,55], one cefalothin combined with kanamycin [37] and one cefotetan with imipenem/tobramycin [39]. Four (66.7%) of these six patients were cured.…”

“…In heroin addicts it has been reported to cause endocarditis [54], whilst pneumonia is frequent in CGD [4,66]. It is also common in immunocompromised patients suffering from malignancies [58,62,68], haemoglobinopathies [35] and other types of immunodeficiency [41,52,70].…”

Acute Burkholderia cenocepacia pyomyositis in a patient with cystic fibrosis

“…It is unusual for Bcc to metastasise away from the lungs but extra-pulmonary sites of infection in non-CF individuals have included the endocardium, peritoneum, wounds, urogenital tract, bones, joints and central nervous system [6]. There have been reports of Bcc related abscesses in the spleen, liver, brain, skin, spinal cord, bladder wall and lung [7][8][9][10][11][12]. A Bcc chest wall abscess in a person with CF has been described [13].…”

“…Although a small number of cases of abscess formation have been described in at-risk groups extra-pulmonary manifestations are unusual [7][8][9][10][11][12][13]. We report a case of acute Bcc pyomyositis.…”