“…Compton cameras (CCs) are electronically collimated gamma-ray imagers which have found application in domains as diverse as astronomy (Schönfelder et al 1973, 1996, De Angelis et al 2017, Rando 2017 or environmental radiation monitoring, including homeland security, nuclear decommissioning and waste management (Martin et al 1994, Wahl et al 2015, Takeda et al 2015, Montémont et al 2017, Hmissi et al 2018, Sinclair et al 2020. CCs applicability to nuclear medical imaging was soon recognized (Todd et al 1974), and their potential advantages as replacement to conventional gamma cameras for diagnostic purposes is well established in the literature (Singh 1983, Zhang et al 2004, Nurdan et al 2015, Fontana et al 2017.…”