First In Vitro–In Silico Analysis for the Determination of Antimicrobial and Antioxidant Properties of 2-(4-Methoxyphenylamino)-2-oxoethyl Methacrylate and p-Acetamide
Mehmet Mürşit Temüz,
Nevin Çankaya,
Safiye Elif Korcan
et al.
Abstract:The antibacterial,
antifungal, and antioxidant activities of 2-chloro-N-(4-methoxyphenyl)acetamide (p-acetamide)
and 2-(4-methoxyphenylamino)-2-oxoethyl methacrylate (MPAEMA) were
investigated by in vitro experiments and in silico analyses. MPAEMA has an antibacterial effect only
against Gram-positive Staphylococcus aureus. It was determined that this did not affect any other bacteria and Candida glabrata yeast. On the other hand, p-acetamide showed antimicrobial activity against S. aureus ATCC 25923, C. glabr… Show more
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