First Follow up Response Evaluation of Conventional vs Drug Eluting Bead Transarterial Chemo Embolization: A Comparative Study at Tertiary Care Radiology Centre, Rawalpindi

Abstract

Objective: To compare treatment with drug eluting beads Transarterial Chemoembolization (DEB TACE) vsConventional Transarterial chemoembolization (cTACE) in hepatocellular carcinoma (HCC) patients at firstfollow up.Study Design: Comparative Interventional Study.Place and Duration of Study: The study was conducted in the department of Radiology CMH Rawalpindiand Armed Forces Institute of Radiology and Imaging (AFIRI), Rawalpindi from July 2015 to May 2019.Materials and Methods: 254 patients were included in the study. Conventional TACE was done on 176 patientsand DEB TACE was done on 78 patients. All patients were called for follow up after 06 weeks. First responseevaluation of treated lesions in these patients was seen on triphasic CT liver after 06 weeks of TACE therapy.Results: On first follow up, out of 176 patients with cTACE, 'Total response' was seen in 90(51.1%) patients,'Partial response' in 76 patients (43.1%),'No response' in 04(2.27%) patients.' Progressive disease' was seen in06(3.4%) patients.DEB TACE was done in 78 patients. Out of these, 27 (34.6%) patients showed 'Total response'. 50(64.1%)patients showed 'Partial response', 'Progressive disease' was seen in one patient (.02%).Conclusion: The findings of this study have shown that c TACE has a better outcome regarding first responseevaluation. 'No response' to treatment was not seen in any patient with DEB TACE.