First direct aromatic ring cleavage of phenols related to vanillin into muconic acid derivatives catalyzed by a microorganism

Artaud, Isabelle; Tomasi, Isabelle; Martin, Gaëlle; Petre, Dominique; Mansuy, Daniel

doi:10.1016/0040-4039(94)02382-l

Cited by 4 publications

(1 citation statement)

References 15 publications

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“…Alternatively, microorganisms can also catalyze the ring cleavage of vanillin. For instance, Artaud and coworkers reported the oxidative conversion of the vanillin moiety into a diene chromophore using Pseudomonas cepacia as catalyst ( Artaud et al, 1995 ). Similarly, the Lentinus edodes enzyme was able to perform the aromatic ring oxidation of vanillin-like compounds ( Crestini et al, 1995 ).…”

Section: Oxidative Ring Openingmentioning

confidence: 99%

Vanillin: A Promising Biosourced Building Block for the Preparation of Various Heterocycles

Gendron

2022

Front. Chem.

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The preparation of heterocyclic compounds often involves the use of petroleum-based or non-renewable sources. Considering the actual societal and environmental awareness towards sustainable chemistry, new and green sources of organic carbon are sought. In this regard, vanillin is a molecular building block that can be obtained from the depolymerization of lignin. Due to its different functional groups (hydroxyl, aldehyde, and methoxy) vanillin can undergo a variety of reactions leading to various heterocycles such as pyrimidines, quinoxalines, imidazoles or thiazoles to name a few. This mini-review will focus on the preparation of accessible heterocycles building blocks from the vanillin moiety in regard to the medicinal, pharmaceutical, and material fields.

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Section: Oxidative Ring Openingmentioning

confidence: 99%