First detection of Macrorhabdus ornithogaster in wild Eurasian Siskins (Carduelis spinus) in Germany

Legler, Marko; Stelter, Robert; Jung, Arne; Wohlsein, P.; Kummerfeld, N

doi:10.15654/tpk-140714

Tierarztl Prax Ausg K

2015

DOI: 10.15654/tpk-140714

|View full text |Cite

First detection of Macrorhabdus ornithogaster in wild Eurasian Siskins (Carduelis spinus) in Germany

Marko Legler¹,

Robert Stelter²,

Arne Jung³

et al.

Abstract: Infections with M. ornithogaster can be found in the wild population of Eurasian Siskins in Germany. The frequent occurrence of secondary bacterial infections associated with M. ornithogaster infections should be considered in the treatment and rehabilitation of finches.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2017

2022

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 11 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Evidence of amphotericin B resistance in Macrorhabdus ornithogaster in Australian cage-birds

et al. 2018

View full text Add to dashboard Cite

Amphotericin B is widely used for the treatment of Macrorhabdus ornithogaster infections. To date, however, there have been no randomized controlled trials confirming its efficacy where cure was confirmed by postmortem examination. To determine the efficacy of amphotericin B against M. ornithogaster, a three-part study was undertaken. Treatment outcomes of M. ornithogaster infected birds treated amphotericin B were reviewed. A pilot treatment trial with two naturally infected birds (Melopsittacus undulatus and Agapornis roseicollis) was undertaken, administering amphotericin B at 100 mg/kg twice daily for 30 days. Finally, a randomized controlled trial using experimentally infected chickens treated with amphotericin B at 25 mg/kg and 100 mg/kg twice daily for 10 days was performed. Retrospective analysis indicated treatment failure in 80.4% of 36 cases that met the inclusion criteria. The pilot study showed that amphotericin B did not clear, but significantly decreased Macrorhabdus ornithogaster burden, followed by profound rebound effect of the number of organisms shed in the feces. Finally, the randomized controlled trial found that amphotericin B given at 100 mg/kg did not clear, but significantly decreased the burden of M. ornithogaster compared with both the 25 mg/kg group (P = .037) and the no treatment control group (P = .001). A strong curvilinear correlation between body weight and M. ornithogaster infection burden was present in the infected chickens. These findings represent treatment failure in three scenarios and indicate that treatment with amphotericin B has poor efficacy against Macrorhabdus ornithogaster.

show abstract

Evidence of amphotericin B resistance in Macrorhabdus ornithogaster in Australian cage-birds

et al. 2018

View full text Add to dashboard Cite

show abstract

The Incidence and Treatment Outcomes ofMacrorhabdus ornithogasterInfection in Budgerigars (Melopsittacus undulatus) in a Veterinary Clinic

Püstow¹,

Krautwald‐Junghanns²

2017

Journal of Avian Medicine and Surgery

View full text Add to dashboard Cite

Macrorhabdus ornithogaster, avian gastric yeast, is a common cause of gastrointestinal disease in budgerigars ( Melopsittacus undulatus). To better understand the clinical disease in budgerigars presented in a practice population, we reviewed the occurrence, clinical signs, and treatment success of M ornithogaster disease in budgerigars during a 2.5-year period at the Clinic for Birds and Reptiles, University of Leipzig (Leipzig, Germany). The yeast was diagnosed by microscopic examination of fresh fecal samples. Male budgerigars of all ages were most affected. Most clinical signs in birds with confirmed positive results were nonspecific, except for the occurrence of undigested seeds in the feces. Although radiographic appearance of a dilated proventriculus is indicative of a M ornithogaster infection, it is difficult to recognize because of the small size of the budgerigars. Birds with positive results were treated with amphotericin B (100 mg/kg PO q12h) for 4 weeks. Treatment was stressful for the birds because of the handling required and the long treatment duration, and therapeutic results were unsatisfactory. Therefore, the indications for treatment with amphotericin B should be carefully considered in birds with positive M ornithogaster results. An increased occurrence of the infection in association with other pathogens was detected.

show abstract

Multiple Epidemics in Austrian Fringillidae Caused by a Single Variant of Salmonella Typhimurium

Brunthaler

Spergser

Weißenböck

2021

Journal of Wildlife Diseases

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

First detection of Macrorhabdus ornithogaster in wild Eurasian Siskins (Carduelis spinus) in Germany

Abstract: Infections with M. ornithogaster can be found in the wild population of Eurasian Siskins in Germany. The frequent occurrence of secondary bacterial infections associated with M. ornithogaster infections should be considered in the treatment and rehabilitation of finches.

Cited by 4 publications

References 11 publications

Evidence of amphotericin B resistance in Macrorhabdus ornithogaster in Australian cage-birds

Evidence of amphotericin B resistance in Macrorhabdus ornithogaster in Australian cage-birds

The Incidence and Treatment Outcomes ofMacrorhabdus ornithogasterInfection in Budgerigars (Melopsittacus undulatus) in a Veterinary Clinic

Multiple Epidemics in Austrian Fringillidae Caused by a Single Variant of Salmonella Typhimurium

Contact Info

Product

Resources

About