First consumption ever of multiple substances: Applying an expert-based taxonomy to a Swiss national sample of adolescents

Berchtold, André; Akré, Christina; Jeannin, André; Michaud, Pierre‐André; Surı́s, Joan-Carles

doi:10.1016/j.addbeh.2010.08.023

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…Diabetic patients undergoing insulin treatment are at increased risk of developing HCC because of the mitogenic effects of high insulin [120]. Patients with diabetes are also more likely to have hepatic steatosis [121,122], and a fatty liver may increase liver cancer risk through excess inflammation, oxidative stress, and other mechanisms [123][124][125][126]. Steatosis can lead to nonalcoholic steatohepatitis and even to fibrosis, cancer, and cirrhosis of the liver.…”

Section: Diabetes Alcohol and Liver Cancermentioning

confidence: 99%

Association of Diabetes Mellitus and Alcohol Abuse with Cancer: Molecular Mechanisms and Clinical Significance

Lam

Srivastava

Morvant

et al. 2021

Cells

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Diabetes mellitus (DM), one of the metabolic diseases which is characterized by sustained hyperglycemia, is a life-threatening disease. The global prevalence of DM is on the rise, mainly in low- and middle-income countries. Diabetes is a major cause of blindness, heart attacks, kidney failure, stroke, and lower limb amputation. Type 2 diabetes mellitus (T2DM) is a form of diabetes that is characterized by high blood sugar and insulin resistance. T2DM can be prevented or delayed by a healthy diet, regular physical activity, maintaining normal body weight, and avoiding alcohol and tobacco use. Ethanol and its metabolites can cause differentiation defects in stem cells and promote inflammatory injury and carcinogenesis in several tissues. Recent studies have suggested that diabetes can be treated, and its consequences can be avoided or delayed with proper management. DM has a greater risk for several cancers, such as breast, colorectal, endometrial, pancreatic, gallbladder, renal, and liver cancer. The incidence of cancer is significantly higher in patients with DM than in those without DM. In addition to DM, alcohol abuse is also a risk factor for many cancers. We present a review of the recent studies investigating the association of both DM and alcohol abuse with cancer incidence.

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Section: Diabetes Alcohol and Liver Cancermentioning

confidence: 99%

Association of Diabetes Mellitus and Alcohol Abuse with Cancer: Molecular Mechanisms and Clinical Significance

Lam

Srivastava

Morvant

et al. 2021

Cells

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“…This is especially true for substance use, since the earlier a person is introduced to substance use, the more likely s/he is to develop addictions later on [5]. Without fully following the gateway theory [6,7], we may say that adolescents commonly experiment with several substances, either successively or simultaneously, and specific patterns of substance initiation can be identified [8]. Moreover, the number of different substances (especially synthetic ones) and their availability seem to have increased during the last few decades [9], and the development of products such as energy drinks, alcopops (mixes of soda with strong alcohol), e-cigarettes and legal cannabis (cannabis without THC) is considered by experts to provide new ways of introducing young people to substance use [10,11].…”

Section: Adolescence and Substance Experimentationmentioning

confidence: 99%

Substance use as a function of activity level among young Swiss men

Diatta

Berchtold

2020

Swiss Med Wkly

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Adolescence is a period of life during which many people experiment with different kinds of legal and illegal substances. However, young people practising physical activities at a high level should avoid taking such substances. On the basis of a large sample of Swiss male recruits (C-SURF baseline data), we explore the consumption of substances among three subgroups of young adults, defined according to level of physical activity: high, medium, and low.Our results show that respondents classified into the high level of physical activity group went through the same experimentation processes with substances as respondents in the other groups, but that they reduced their overall consumption level, as indicated by measures regarding the last 12 months only. However, substantial differences are observed when we look at each substance separately. In particular, smokeless tobacco products are consumed more in the high group, and alcohol consumption is high in all groups.Physical activity, even at a high level, is not a protective factor against substance consumption. Therefore, physicians should not forget to investigate substance use among people with high levels of physical activity, especially since their consumption can (1) differ from the general population; and (2) have important consequences on their physical performance.

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Age of First Use, Age of Habitual Use, and Problematic Alcohol Use: a Cross-cultural Examination Among Young Adults in Seven Countries

Chentsova

Bravo

Pilatti

et al. 2023

Int J Ment Health Addiction

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First consumption ever of multiple substances: Applying an expert-based taxonomy to a Swiss national sample of adolescents

Cited by 3 publications

References 30 publications

Association of Diabetes Mellitus and Alcohol Abuse with Cancer: Molecular Mechanisms and Clinical Significance

Association of Diabetes Mellitus and Alcohol Abuse with Cancer: Molecular Mechanisms and Clinical Significance

Substance use as a function of activity level among young Swiss men

Age of First Use, Age of Habitual Use, and Problematic Alcohol Use: a Cross-cultural Examination Among Young Adults in Seven Countries

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