First Chemosensor for Selective Detection and Quantification of L-4-Hydroxyproline in Collagen and Other Bio Samples

Abstract

Amino pyridine-based rhodamine conjugate (APR) has been developed as a first chemosensor for selective detection and quantification of L-4-Hydroxyproline (Hyp). The "turn-on" fluorescence property of the chemosensor makes it unique for easy estimation of Hyp in collagen and biological samples.

Extraction and Properties of Acid-Soluble Collagen and Pepsin-Soluble Collagen from Silver Carp (Hypophthalmichthys molitrix) Scales: Prerequisite Information for Fishery Processing Waste Reuse

“…Obviously, the scales are mainly composed of protein and ash. Hydroxyproline is a characteristic amino acid of collagen, and therefore the approximate content of collagen in the scales can be calculated from the hydroxyproline content, and the conversion factor for aquatic animals is usually 11.1 [16]. As the hydroxyproline content is as high as 3.35%, the content of collagen in the scales is approximately 37.19%, accounting for 77.34% of the protein.…”

Differential detection of aspartic acid in MCF-7 breast cancer cells

“…Due to their simplicity, high selectivity, sensitivity, low cost, easy implementation, and real-time detection, it is always preferable to use chemosensors as an expedient tool in biological and clinical examination. [22][23][24][25][26][27][28][29] Herein, we report a pyridine-carbazole framework (PCF) to detect aspartic acid in live cell systems. The PCF probe has been characterized using UV-visible, fluorescence, 1 H NMR, 13 C NMR, and high-resolution mass spectrometry spectra, for C 20 H 18 N 3 with calc.…”

“…Due to their simplicity, high selectivity, sensitivity, low cost, easy implementation, and real-time detection, it is always preferable to use chemosensors as an expedient tool in biological and clinical examination. 22–29…”

Highly Selective Optical and Fluorescence “Turn On” Signaling of Al3+: Cell Imaging and Estimation in Rice Plant

“…In recent years certain analytical approaches have been reported for the detection and quantification of bio‐relevant metal ions, but many of them are associated with various crucial drawbacks . But chemosensors based on fluorescent and optical signaling method turn out to be a promising device owing to its remarkable selectivity and sensitivity, portability, low cost, instant responds, naked eye detection facilities to estimate metal ions in analytical, medical, environmental and biological fields . However the detection of Al is always challenging than the other metal ions due to its high hydration ability in water, poor coordination ability and lack of spectroscopic characterization, thus development of a simple but very precise chemosensor for Al detection is a significant domain of research.…”