First Case Report of Locally Advanced Malignant Nodular Hidradenoma of the Scrotum

Abstract

Background: Malignant nodular hidradenoma (MNH) is a malignant tumor of the eccrine glands, and most commonly involves the head, trunk, and extremities. To the best of our knowledge, MNH of the scrotum has not yet been described in the English literature. Despite the use of surgery, chemotherapy, radiotherapy, and hormonal therapy, optimal treatment of MNH is unclear. Case Report: We describe the case of a 30-year-old African American man who was diagnosed with locally advanced MNH of the scrotum and treated with surgery. More than 2 years after surgery, the patient is without evidence of disease. Conclusions: This is the first case report of MNH of the scrotum. Surgery alone may be sufficient for the treatment of localized or locally advanced MNH.

A weeping tumor in a young girl: An unusual presentation of nodular hidradenoma

“…[ 2 ] Malignant transformation with metastasis has been reported. [ 7 8 ] Our case was characterized by unusual histological features. It was predominantly composed of a cell type having finely granular, faintly eosinophilic cytoplasm with a dark-colored round to oval nucleus.…”

Hidradenocarcinoma do Escroto com Metastização Ganglionar

“…A recorrência local pode ocorrer em cerca de 50% dos casos após ressecção cirúr-gica alargada e, em 60% dos doentes aparecem metásta-ses nos primeiros dois anos. 6 A sobrevida aos cinco anos é de 30% -74%, inferior aos restantes tumores dos anexos cutâneos com diferenciação écrina. 3,4 A biópsia do gânglio sentinela pode ser útil para estadiamento, mas o impacto não foi comprovado na sobrevida.…”