First case report of empyema caused by Beauveria bassiana

Abstract

Infections with Beauveria bassiana are extremely rare in humans. A 51-year-old man was admitted to hospital with the diagnosis of lung adenocarcinoma. Thoracic wall resection with lobectomy was applied and empyema has developed after prolonged air leakage. B. bassiana was isolated in pleural fluid. The patient improved without antifungal therapy after thoracotomy with securing of air leakage.

Recalcitrant Beauveria bassiana Keratitis

“…1,5,10 Two of these cases were in severely immunocompromised patients. 5,10 A B. bassiana empyema described in an immunocompetent patient responded to drainage without antifungal therapy.…”

“…1 Three case reports of B. bassiana keratitis have been reported previously, 2 requiring surgical extirpation and 1 responding to medical therapy. [2][3][4] We report a case of B. bassiana keratitis with confocal and histologic smear findings failing multiple topical and systemic antifungal medications and treated successfully with the addition of oral posaconazole to topical voriconazole.…”

Beauveria Keratitis and Biopesticides: Case Histories and a Random Amplification of Polymorphic DNA Comparison

“…This correlates with a case report from Turkey describing a patient who underwent a thoracic wall resection with lobectomy and developed a postoperative empyema attributed to B. bassiana. 25 Beauveria and other fungi are used as biopesticides worldwide. In a review article about human exposure to fungi used in biocontrol agents, Madsen et al 1 report that Beauveria has been found in indoor environments, is often isolated from insects and soil samples, and because conidia are presumably dispersed by air currents, it may occur in air where insect hosts live.…”

A study on the fungi isolated from the carpeting, walls and Holy Qurans from the Blue Mosque and Little Hagia Sophia Mosque situated in the province of Istanbul

“…The probability of airborne saprophytic fungi causing invasive disease in individuals who otherwise have a healthy immune system is low. However, for those with pre-existing conditions, the potential for a disease to arise is quite high (Gürcan et al, 2006). Thus this is why it is imperative that the fungal concentration in such highly populated buildings such as hospitals (Sarica et al, 2002), schools (Hargreaves, 2003) and pre-school crèche facilities (Aydogdu and Asan, 2008) is researched.…”