First case of percutaneous left atrial appendage closure by amulet™ device in a patient with left atrial appendage thrombus

Aytemir, Kudret; Aminian, Adel; Asil, Serkan; Canpolat, Uğur; Kaya, Ergün Barış; Şahiner, Levent; Evranos, Banu; Yorgun, Hikmet; Özer, Necla

doi:10.1016/j.ijcard.2016.08.171

Cited by 15 publications

(10 citation statements)

References 4 publications

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“…Available data about LAA closure in patients with thrombus are sparse and limited to case reports and very small case series (Table 5) [15][16][17][18][19][20][21][22][23][24][25] . These have all reported procedural success using a minimal manipulation implantation technique or inconstant use of a cerebral embolic protection device.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous left atrial appendage occlusion in patients with atrial fibrillation and left appendage thrombus: feasibility, safety and clinical efficacy

Tarantini¹,

D’Amico²,

Latib³

et al. 2018

EuroIntervention

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In this multicentre study, percutaneous closure in selected patients with distal LAA thrombus appears to be feasible and safe, and is associated with high procedural success and a favourable outcome for the prevention of AF-related thromboembolism. Special implant techniques avoiding mechanical mobilisation of the thrombotic mass and the liberal use of cerebral embolic protection devices are recommended.

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Section: Discussionmentioning

confidence: 99%

Percutaneous left atrial appendage occlusion in patients with atrial fibrillation and left appendage thrombus: feasibility, safety and clinical efficacy

Tarantini¹,

D’Amico²,

Latib³

et al. 2018

EuroIntervention

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“…Despite the aforementioned data, only a few case reports are describing the safe elimination of the LAA in the case of a thrombus in its proximal part [5][6][7]. Performing such a procedure requires much experience and precision.…”

Section: Discussionmentioning

confidence: 99%

Rationale for cerebral protection in patients with left atrial appendage thrombus during percutaneous left atrial appendage closure: a single-center initial experience

Streb

Mitręga

Podolecki

et al. 2020

Polish Archives of Internal Medicine

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“…We have reported one of these cases previously. 22 Tarantini et al 23 recently reported in their multicenter study that LAA occlusion could be safely and effectively performed in 28 patients with distal LAA thrombus. 23 In line with these findings, we also suggest that LAA occlusion could be successfully conducted in patients with distal thrombus in experienced centers.…”

Section: Discussionmentioning

confidence: 99%

Left Atrial Appendage Transcatheter Occlusion with AMPLATZERT AmuletT Device: Real Life Data with Mid-Term Follow-Up Results

Şahiner

Kaya

Çöteli

et al. 2019

Arquivos Brasileiros De Cardiologia

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Background: Left atrial appendage (LAA) occlusion is an alternative therapy for atrial fibrillation patients who have high embolic risk and contraindications to anticoagulant therapy.Objective: To evaluate the feasibility, safety, and mid-term outcomes of percutaneous LAA occlusion, including device-related thrombosis.Methods: Sixty consecutive patients who had undergone percutaneous LAA occlusion with AMPLATZER™ Amulet™ device from September 2015 to March 2018 were enrolled. Patients were followed for 21 ± 15 months (median -20 months, interquartile range -9 to 27 months). The postprocedural assessment was done at the 1 st , 6 th , and 12 th month. Patients were clinically evaluated, and transesophageal echocardiography was performed at each visit. We evaluated the condition of normality of variables using the Kolmogorov-Smirnov test. P-values < 0.05 were statistically significant.Results: The most common indication for the procedure was major bleeding with anticoagulants (n: 53, 88.3%). The procedure was completed successfully in 59 (98.3%) patients. Periprocedural mortality was observed in one patient. Postprocedural antiplatelet treatment was planned as dual or single antiplatelet therapy or low-dose anticoagulant therapy in 52 (88.1%), 2 (3.4%), and 5 (8.5%) patients, respectively. We found no clinically significant cerebrovascular events, device-related thrombus, or embolization in any patient during the follow-up. Two (3.4 %) patients presented significant peri-device leak (>3 mm) at the 1 st month evaluation, which disappeared at the 12 th month follow-up. Conclusion:We concluded that LAA occlusion using the Amulet™ LAA occluder can be performed with high procedural success and acceptable outcomes.

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First case of percutaneous left atrial appendage closure by amulet™ device in a patient with left atrial appendage thrombus

Cited by 15 publications

References 4 publications

Percutaneous left atrial appendage occlusion in patients with atrial fibrillation and left appendage thrombus: feasibility, safety and clinical efficacy

Percutaneous left atrial appendage occlusion in patients with atrial fibrillation and left appendage thrombus: feasibility, safety and clinical efficacy

Rationale for cerebral protection in patients with left atrial appendage thrombus during percutaneous left atrial appendage closure: a single-center initial experience

Left Atrial Appendage Transcatheter Occlusion with AMPLATZERT AmuletT Device: Real Life Data with Mid-Term Follow-Up Results

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