First case of human spondylodiscitis due to Shewanella algae

Gressier, M; M’bayo, D.; Deramond, H.; Grados, Franck; Eb, F.; Canarelli, B.

doi:10.1016/j.ijid.2009.11.007

Cited by 20 publications

(18 citation statements)

References 26 publications

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“…16 μg/mL; intermediate, 32- μg/mL) and trimethoprim-sulfamethoxazole (susceptible, ! 2/ 38 μg/mL; resistant, " 4/76 μg/mL) were interpreted using CLSI approved standard M100-S22 categories for other nonEnterobacteriaceae in accordance with previous reports (7,9,14). In addition, the standards recommended by the U.S. Food and Drug Administration (FDA) for ampicillin/sulbactam (susceptible, !…”

Section: Methodsmentioning

confidence: 99%

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Clinical and Microbiological Features of <i>Shewanella</i> Bacteremia in Patients with Hepatobiliary Disease

et al. 2013

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Objective Shewanella bacteremia is an uncommon but potentially fatal disease. Although hepatobiliary diseases have been proposed to be risk factors for various Shewanella infections, little is known about the features of Shewanella bacteremia in patients with hepatobiliary diseases. This study aims to characterize the presentation and risk factors of Shewanella bacteremia in patients with hepatobiliary diseases. Methods We retrospectively investigated the clinical features, microbiology and outcomes of patients with Shewanella bacteremia who were admitted to a tertiary medical center between January 2001 and December 2010. All isolates were confirmed to the species level using 16S rRNA sequencing analyses. The English language medical literature was searched for previously published reports. Results Fifty-nine cases of Shewanella bacteremia, including nine at the hospital, were identified, 28 (47.4%) of which involved underlying hepatobiliary diseases, representing an important risk factor. In 12 of the 28 cases, the infections involved the hepatobiliary system; with a tendency towards an Asian origin. In our case series of nine patients, Shewanella haliotis was isolated in five patients. The majority of our patients lived in coastal areas, consumed seafood regularly and developed bacteremia during the summer season. Conclusion It is recommended that the possibility for Shewanella infection be considered in patients with bacteremia and also underlying hepatobiliary diseases, particularly if patients present with hepatobiliary infections, a history of seafood, or development of the disease during the summer.

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Section: Methodsmentioning

confidence: 99%

“…By incorporating 16S rRNA gene sequencing into the identification of Shewanella, more Shewanella species can be recognized as pathogenic organisms (5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

Clinical and Microbiological Features of <i>Shewanella</i> Bacteremia in Patients with Hepatobiliary Disease

et al. 2013

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“…S. algae , a member of the Shewanella genus, can cause human diseases, such as spondylodiscitis and bloody diarrhea [19]–[21]; therefore, it has attracted much attention in microbiology. S. algae strains that produce tetrodotoxin and exist in various seafood are recently obtained from anal swabs of patients with food poisoning [22], [23], and the strains are able to grow in high salt levels.…”

Section: Introductionmentioning

confidence: 99%

Time Course Transcriptome Changes in Shewanella algae in Response to Salt Stress

Wang

Yin

et al. 2014

PLoS ONE

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Shewanella algae, which produces tetrodotoxin and exists in various seafoods, can cause human diseases, such as spondylodiscitis and bloody diarrhea. In the present study, we focused on the temporal, dynamic process in salt-stressed S. algae by monitoring the gene transcript levels at different time points after high salt exposure. Transcript changes in amino acid metabolism, carbohydrate metabolism, energy metabolism, membrane transport, regulatory functions, and cellular signaling were found to be important for the high salt response in S. algae. The most common strategies used by bacteria to survive and grow in high salt environments, such as Na+ efflux, K+ uptake, glutamate transport and biosynthesis, and the accumulation of compatible solutes, were also observed in S. algae. In particular, genes involved in peptidoglycan biosynthesis and DNA repair were highly and steadily up-regulated, accompanied by rapid and instantaneous enhancement of the transcription of large- and small-ribosome subunits, which suggested that the structural changes in the cell wall and some stressful responses occurred in S. algae. Furthermore, the transcription of genes involved in the tricarboxylic acid (TCA) cycle and the glycolytic pathway was decreased, whereas the transcription of genes involved in anaerobic respiration was increased. These results, demonstrating the multi-pathway reactions of S. algae in response to salt stress, increase our understanding of the microbial stress response mechanisms.

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“…Shewanella putrefaciens is a Gram-negative, non-fermentative, oxidasepositive, motile bacillus, conditional pathogen. In recent years, some clinical infections caused by Shewanella putrefaciens were reported, [2][3][4][5] and the bacteria can be isolated from the patients' blood, pus, urine, sputum and wound secretions. This is the first time in our hospital that Shewanella putrefaciens in the cerebrospinal fluid specimen was detected.…”

Section: Discussionmentioning

confidence: 99%

A case report of intracranial infection caused by Shewanella putrefaciens

Duan

Wang²,

Wang

et al. 2014

Neurol Sci

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Shewanella putrefaciens is as yet reputed to be a rare conditional pathogen. In recent years, some clinical infections caused by Shewanella putrefaciens came into view, and it was possible for the bacteria to be isolated from blood, pus, urine, sputum, and wound secretions, etc. A transferred patient who suffered from intracranial infection after operation of cerebral hemorrhage was admitted in the First Affiliated Hospital of Dalian Medical University. To ascertain the cause, we assessed her blood, cerebrospinal fluid and sputum specimen, and succeeded in isolating one strain of bacteria from her cerebrospinal fluid. To circumvent the potential problem, further detection by Dade Behring Microscan WalkAway 96SI system and drug sensitivity identification plate was performed. Corresponding results indicated that the bacteria were certain pseudomonas with high drug resistance, only sensitive to ticarcillin/clavulanic acid and Imipenem. Eventually by 16S rDNA amplification assay, a new technique to identify pathogens genome, Shewanella putrefaciens infection was confirmed with 99 % coincidence rate. This is the first time in our hospital that Shewanella putrefaciens in the cerebrospinal fluid specimen was detected. When considering the increase of opportunistic infection, it is noteworthy to pay more attention to such situations in clinical diagnoses.

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First case of human spondylodiscitis due to Shewanella algae

Cited by 20 publications

References 26 publications

Clinical and Microbiological Features of <i>Shewanella</i> Bacteremia in Patients with Hepatobiliary Disease

Clinical and Microbiological Features of <i>Shewanella</i> Bacteremia in Patients with Hepatobiliary Disease

Time Course Transcriptome Changes in Shewanella algae in Response to Salt Stress

A case report of intracranial infection caused by Shewanella putrefaciens

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