First Case of Degenerative Mucinotic Mural Folliculitis in Brazil

Filho, Reginaldo Pereira de Sousa; Rolim, Verônica Machado; Sampaio, Keytyanne de Oliveira; Driemeier, David; Cunha, Marina Gabriela Monteiro Carvalho Mori da; Costa, Fernanda Vieira Amorim da

doi:10.15226/2381-2907/2/2/00118

Cited by 3 publications

(9 citation statements)

References 5 publications

(12 reference statements)

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“…survival time ranging from 2 weeks to 5 months from the start of treatment. [1][2][3] However, in the case of early-onset degenerative mucinotic mural folliculitis reported by Vacheva, 4 the survival time from the start of treatment was 12 months. In the present early-onset case, the cat was still alive 14 months after the start of treatment.…”

Section: Discussionmentioning

confidence: 99%

“…In previous reports of degenerative mucinotic mural folliculitis, the age at onset ranged from 3 to 12 years, with most patients being middle-aged or older. [1][2][3] However, a case of early-onset degenerative mucinotic mural folliculitis was reported, in which the age at onset was 1.4 years. 4 The age at onset in the present case was 1.5 years, corresponding to early onset in previous studies.…”

Section: Discussionmentioning

confidence: 99%

“…Most cats unresponsive to treatment were euthanased 2-8 weeks after the diagnosis. With respect to corticosteroid injections, Gross et al 1 reported improvement in hair growth with lipositol, whereas de Sousa Filho et al 3 reported improvement with methylprednisolone. However, the cat in the report by Gross et al 1 was euthanased 5.0 months after the start of treatment because of oral ulcers, and the cat in the report by de Sousa Filho et al 3 died 3.3 months after the start of treatment because of worsening of its general condition.…”

Section: Discussionmentioning

confidence: 99%

“…With respect to corticosteroid injections, Gross et al 1 reported improvement in hair growth with lipositol, whereas de Sousa Filho et al 3 reported improvement with methylprednisolone. However, the cat in the report by Gross et al 1 was euthanased 5.0 months after the start of treatment because of oral ulcers, and the cat in the report by de Sousa Filho et al 3 died 3.3 months after the start of treatment because of worsening of its general condition. Ogaya et al 2 reported that combined treatment with triamcinolone acetonide (0.7 mg/kg) and ciclosporin (8 mg/kg) administered once daily resulted in mild improvement of cutaneous signs.…”

Section: Discussionmentioning

confidence: 99%

“…Gross et al 1 comprehensively described this condition in 2001, and only a few case reports have since been published. [2][3][4] Although its cause has not yet been identified, immune abnormalities may be involved. 5 Degenerative mucinotic mural folliculitis is a severe form of mural folliculitis in cats, and is considered to be a distinct entity.…”

Section: Introductionmentioning

confidence: 99%

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Effect of ciclosporin on clinical signs of degenerative mucinotic mural folliculitis in a young cat

Mizoguchi,

Fujiwara,

Sekiguchi

et al. 2023

Vet Record Case Reports

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A 1.5‐year‐old, spayed, female, mixed‐breed cat that had been housed completely indoors presented with a chief complaint of facial hair loss. Alopecia extended from the face to the outside of the auricle, and was accompanied by thickening of the dorsal eyelid and scales on the dorsal chest. Histopathological examination revealed infiltration of lymphocytes targeting the hair follicle wall and deposition of mucin in the isthmus of hair follicles. A diagnosis of degenerative mucinotic mural folliculitis was obtained based on the clinical and histological findings. The cat was treated with ciclosporin (9.3 mg/kg) administered once daily. The alopecia and thickening resolved, and the general condition improved. The cat was clinically well for 10 months. The cat has survived 14 months since treatment was started. This case demonstrates the efficacy of high‐dose ciclosporin in treating degenerative mucinotic mural folliculitis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%