Nowadays, firms are keen to combine artificial intelligence with machine learning to improve productivity. More precisely, artificial intelligence and machine learning play a variety of functions in business, from improving communication between staff and customers to automating repetitive tasks. The chapter investigates the impact of artificial intelligence on job performance, using employees' characteristics and types of sectors as mediators' variables. Both explanatory and confirmatory factor analyses, as well as structural equation modeling, are used in the study. The authors found that artificial intelligence has no impact on job performance. Indeed, both employees' characteristics and types of sectors do not mediate the relationship between artificial intelligence and job performance.