“…2 It is worth noting that patients with OA who had comorbid psychiatric conditions might be prescribed SNRIs, potentially serving as a proxy for mental health that could significantly influence social behavior and participation. Additionally, socioeconomic status was addressed in the study, but other prevalent elderly diseases such as hypertension, 3,4 hyperlipidemia, 5 dementia, 6 sleep disorders, 7 and rheumatoid arthritis, 8 which frequently coexist with OA, and other conditions such as the coronavirus disease 2019 (COVID-19) 9,10,11 that can profoundly impact social participation,…”