Finger-tapping Motion Analysis in Cervical Myelopathy by Magnetic-Sensor Tapping Device

Miwa, Toshitada; Hosono, Noboru; Mukai, Yoshihiro; Makino, Takahiro; Kandori, Akihiko; Fuji, Takeshi

doi:10.1097/bsd.0b013e31828d6a44

Cited by 11 publications

(9 citation statements)

References 16 publications

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“…FRDA patients consistently showed significant FT rate slowing along the tapping sequence, which is typical of pyramidal impairment. 12 This abnormality was more severe in those with higher SARA scores and disease duration. Progressive pyramidal tracts involvement in FRDA is supported by neuropathological, clinical, and electrophysiological findings 32,33 Weakness, spasticity, and muscle atrophy of the hands are eventually found in over two-third of cases.…”

Section: Discussionmentioning

confidence: 95%

“…Even a semi-automated score like the CCSF, which is now included in several ataxia studies, 26,27 has limitations in this regard because it focuses on the time needed to perform brief manual tasks, a parameter that alone cannot discriminate among different causes of movement slowing. [6][7][8]12,28 We used a method that analyzes multiple FT movement parameters, allowing to delve deeper into the pathophysiology underlying the observed movement slowing in FRDA patients. First, instead of showing the prominent FT rate variability that characterizes FT impairment in cerebellar disease, 4,6,7 FRDA patients were even more regular than healthy individuals.…”

Section: Discussionmentioning

confidence: 99%

“…5,10,11 Conversely, pyramidal tract lesions cause a progressive decrease in both FT movement amplitude and tapping rate. 12 In cerebellar disease, the most pronounced alteration is the loss of FT tapping regularity, with up to 5-fold increase in the variance of the timing between consecutive tappings. 4,6,7 Friedreich ataxia (FRDA) is the commonest autosomal recessive ataxia in Caucasians.…”

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confidence: 99%

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Hand Dexterity and Pyramidal Dysfunction in Friedreich Ataxia, A Finger Tapping Study

Naeije

Rovaï

Pandolfo

et al. 2020

Movement Disord Clin Pract

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Background Background: Loss of hand dexterity has a profound impact on disability in patients with cerebellar, pyramidal, or extrapyramidal diseases. Analysis of multiple finger tapping (FT) parameters can contribute to identify the underlying physiopathology, while providing a quantitative clinical assessment tool, particularly in patients not reliably evaluated using clinical rating scales. Here, we used an automated method of FT analysis in Friedreich ataxia (FRDA) to disentangle cerebellar (prominent FT rate variability), extrapyramidal (FT progressive amplitude reduction without slowing of tapping rate), and pyramidal (progressive decrease of FT rate and amplitude) contribution to upper limb loss of dexterity. FT parameters were then related to FRDA clinical parameters and upper limbs motor evoked potential (MEPs). Methods Methods: Twenty-four FRDA patients and matched healthy subjects performed FT with the dominant hand for 90 seconds. FT rate, FT rate variability, FT amplitude, and linear regressions of FT movement parameters were automatically computed. Eleven patients underwent MEPs, measured at the first dorsal interosseous of the dominant hand to determine central motor conduction time (CMCT). Results Results: FRDA patients had slower and more regular FT rate than controls. Eleven FRDA patients showed FT rate slowing. Those patients had longer disease duration and higher Scale for the Assessment and Rating of Ataxia (SARA) scores. Seven patients with FT rate slowing had MEP and all displayed prolonged CMCT, whereas the 4 other patients with constant FT rate had normal CMCT. Conclusion Conclusion: This study provides evidence for a prominent involvement of pyramidal dysfunction in upper limb dexterity loss as well as a potential outcome measure for clinical studies in FRDA.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Hand Dexterity and Pyramidal Dysfunction in Friedreich Ataxia, A Finger Tapping Study

Naeije

Rovaï

Pandolfo

et al. 2020

Movement Disord Clin Pract

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“…It suggested that the better the preoperative hand function was, the better the surgical e cacy would be. Besides, the improvement rates of JOA scores was positively correlated with the increased number of cycles in postoperative, which might be the result of restoration of blood circulation in spinal cord after decompression surgery [20]. The fatigue phenomenon in healthy individuals and the freezing phenomenon in patients have been observed by Hosono, N. et al [2].…”

Section: Discussionmentioning

confidence: 74%

Development and Evaluation of a New Assessment Tool for Myelopathy Hand

Zhang

et al. 2020

Preprint

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Background: Impairment of hand function in myelopathy patients is commonly observed. However, no objective and effective evaluation method has been widely accepted in clinical practice. The study aimed to evaluate the validity, reliability and effectiveness of a new assessment tool, Myelopathy-hand Functional Evaluation System (MFES), in evaluating the hand dysfunction of myelopathy-hand in the 10-s hand grip-and-release test (10s G-R test).Methods: MFES mainly consists of a pair of wise-gloves and a computer with software. All included patients received optimal surgery treatment. The Japanese Orthopedic Association (JOA) scores of each patient were marked and the hand function was evaluated using MFES before, and 6 months after surgery. All patients were asked to perform the 10s G-R test and the hand movements were simulated and converted into waveforms by MFES. The waveform parameters were measured and analyzed. The validity and test-retest reliability were assessed.Results: The Bland-Altman showed significant agreement with a low bias and narrow limits of agreement. The test-retest reliability was high with a significant value (r=0.911). The JOA scores and the number of G-R cycles significantly increased after surgery. Correspondingly, the waveforms of ulnar three fingers were significantly higher and narrower, along with the significantly declined average time per cycle in postoperative. The number of the first five-second segment (N1) was significantly higher than the second-five segment (N2) in postoperative, indicating the recovery of spinal cord function after surgery. The preoperative number of cycles was positively correlated with the improvement rates of JOA scores. And the increased number of cycles was significantly correlated with the improvement rates of JOA scores.Conclusion: MFES is a reliable and valid assessment tool for myelopathy hand, which can detect small changes of neurological function after decompression surgery.

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“…It suggested that the better the preoperative hand function was, the better the surgical e cacy would be. Besides, the improvement of JOA scores was positively correlated with the postoperative number of cycles correspondingly increased, which might be the result of restoration of blood circulation in spinal cord after decompression surgery [20]. The fatigue phenomenon in healthy individuals and the freezing phenomenon in patients have been observed by Hosono, N. et al [2].…”

Section: Discussionmentioning

confidence: 76%

Development and Evaluation of a New Assessment Tool for Myelopathy Hand Using Virtual Reality

X¹,

Z²,

Zhang³

et al. 2020

Preprint

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Background: Impairment of hand function in myelopathy patients is commonly observed. However, no objective and effective method is widely accepted in clinical practice.Objective: To evaluate the validity, reliability and effectiveness of a new assessment tool, Myelopathy-hand Functional Evaluation System (MFES), in evaluating the hand function in the 10-s hand grip-and-release test (10s G-R test).Methods: MFES is mainly composed of a pair of wise-gloves and a computer with software. All included patients received optimal surgery treatment. The Japanese Orthopedic Association (JOA) scores were performed and the hand function was evaluated using MFES before operation, and 6 months after surgery. All patients were asked to perform the 10s G-R test and the hand movements were simulated and converted into waveforms by MFES. The waveform parameters were measured and analyzed. The validity and test-retest reliability were assessed.Results: The Bland-Altman showed significant agreement with a low bias and narrow limits of agreement. The test-retest reliability was high with a significant value (r=0.911). The JOA scores and the number of G-R cycles significantly in postoperative increased. Correspondingly, the waveforms of ulnar three fingers were significantly higher and narrower, along with the significantly declined average time per cycle in postoperative. The number of the first five-second segment (N1) was significantly higher than the second-five segment (N2) in postoperative, indicating the recovery of spinal cord function after surgery. The preoperative number of cycles was positively correlated with the improvement rates of JOA scores. And the increased number of cycles was significantly correlated with the improvement rates of JOA scores.Conclusion: MFES is a reliable and valid assessment tool for myelopathy hand, which can detect small changes of neurological function after decompression surgery.

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Finger-tapping Motion Analysis in Cervical Myelopathy by Magnetic-Sensor Tapping Device

Abstract: The quantitative evaluation of finger paralysis was performed by this tapping device. Speed and regularity in repetitive motion of fingers were correlated with the severity of cervical myelopathy.

Cited by 11 publications

References 16 publications

Hand Dexterity and Pyramidal Dysfunction in Friedreich Ataxia, A Finger Tapping Study

Hand Dexterity and Pyramidal Dysfunction in Friedreich Ataxia, A Finger Tapping Study

Development and Evaluation of a New Assessment Tool for Myelopathy Hand

Development and Evaluation of a New Assessment Tool for Myelopathy Hand Using Virtual Reality

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